1CWU
BRASSICA NAPUS ENOYL ACP REDUCTASE A138G MUTANT COMPLEXED WITH NAD+ AND THIENODIAZABORINE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD A 501 |
| Chain | Residue |
| A | GLY25 |
| A | LEU137 |
| A | GLY138 |
| A | LEU186 |
| A | THR187 |
| A | LYS206 |
| A | ALA233 |
| A | GLY234 |
| A | PRO235 |
| A | LEU236 |
| A | SER238 |
| A | ILE26 |
| A | ALA240 |
| A | ALA241 |
| A | ILE247 |
| A | TDB502 |
| A | HOH514 |
| A | HOH528 |
| A | HOH547 |
| A | HOH550 |
| A | GLY31 |
| A | TYR32 |
| A | TRP52 |
| A | ASP89 |
| A | ALA90 |
| A | VAL91 |
| A | SER136 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TDB A 502 |
| Chain | Residue |
| A | GLY138 |
| A | ASN139 |
| A | GLY140 |
| A | TYR188 |
| A | TYR198 |
| A | MET202 |
| A | LYS206 |
| A | ALA240 |
| A | ALA241 |
| A | ILE244 |
| A | NAD501 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD B 503 |
| Chain | Residue |
| B | GLY25 |
| B | ILE26 |
| B | ALA27 |
| B | GLY31 |
| B | TYR32 |
| B | TRP52 |
| B | ASP89 |
| B | ALA90 |
| B | SER136 |
| B | LEU137 |
| B | GLY138 |
| B | LEU186 |
| B | THR187 |
| B | LYS206 |
| B | ALA233 |
| B | GLY234 |
| B | PRO235 |
| B | LEU236 |
| B | SER238 |
| B | ALA240 |
| B | ALA241 |
| B | TDB504 |
| B | HOH522 |
| B | HOH540 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TDB B 504 |
| Chain | Residue |
| B | GLY138 |
| B | TYR198 |
| B | MET202 |
| B | LYS206 |
| B | ALA240 |
| B | ALA241 |
| B | ILE244 |
| B | NAD503 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10521472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10610777","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8535786","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| A | TYR198 | |
| A | LYS206 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| B | TYR198 | |
| B | LYS206 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| A | LYS206 | |
| A | MET202 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1qsg |
| Chain | Residue | Details |
| B | LYS206 | |
| B | MET202 |
