1CTS

CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004108	molecular_function	citrate (Si)-synthase activity
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005975	biological_process	carbohydrate metabolic process
A	0006099	biological_process	tricarboxylic acid cycle
A	0006101	biological_process	citrate metabolic process
A	0016740	molecular_function	transferase activity
A	0036440	molecular_function	citrate synthase activity
A	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CIT A 438

Chain	Residue
A	HIS238
A	ASN242
A	HIS274
A	ARG401

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Functional Information from PROSITE/UniProt

site_id	PS00480
Number of Residues	13
Details	CITRATE_SYNTHASE Citrate synthase signature. GYGHaVl.RktDPR

Chain	Residue	Details
A	GLY317-ARG329

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE:

Chain	Residue	Details
A	HIS274
A	HIS320
A	ASP375

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q29RK1

Chain	Residue	Details
A	LYS49

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9CZU6

Chain	Residue	Details
A	LYS76
A	LYS166
A	LYS423

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9CZU6

Chain	Residue	Details
A	SER199

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site_id	SWS_FT_FI5
Number of Residues	5
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q9CZU6

Chain	Residue	Details
A	LYS294
A	LYS300
A	LYS348
A	LYS366
A	LYS432

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O75390

Chain	Residue	Details
A	LYS355

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site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:7093227

Chain	Residue	Details
A	LYS368

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