1CRK
MITOCHONDRIAL CREATINE KINASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004111 | molecular_function | creatine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0046314 | biological_process | phosphocreatine biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004111 | molecular_function | creatine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005743 | cellular_component | mitochondrial inner membrane |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0046314 | biological_process | phosphocreatine biosynthetic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004111 | molecular_function | creatine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005743 | cellular_component | mitochondrial inner membrane |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| C | 0046314 | biological_process | phosphocreatine biosynthetic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004111 | molecular_function | creatine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005743 | cellular_component | mitochondrial inner membrane |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| D | 0046314 | biological_process | phosphocreatine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 400 |
| Chain | Residue |
| A | ARG127 |
| A | ARG287 |
| A | ARG315 |
| A | ARG336 |
| A | PO4401 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 401 |
| Chain | Residue |
| A | ARG315 |
| A | PO4400 |
| A | ARG125 |
| A | ARG127 |
| A | ARG231 |
| A | ARG287 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 400 |
| Chain | Residue |
| B | ARG127 |
| B | ASN281 |
| B | ARG287 |
| B | ARG315 |
| B | ARG336 |
| B | PO4401 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 401 |
| Chain | Residue |
| B | ARG125 |
| B | ARG127 |
| B | ARG287 |
| B | ARG315 |
| B | PO4400 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 C 400 |
| Chain | Residue |
| C | ARG127 |
| C | ASN281 |
| C | ARG287 |
| C | ARG315 |
| C | ARG336 |
| C | PO4401 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 401 |
| Chain | Residue |
| C | ARG125 |
| C | ARG127 |
| C | ARG287 |
| C | PO4400 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 400 |
| Chain | Residue |
| D | ARG127 |
| D | ASN281 |
| D | ARG287 |
| D | ARG315 |
| D | ARG336 |
| D | PO4401 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 D 401 |
| Chain | Residue |
| D | ARG125 |
| D | ARG127 |
| D | ARG287 |
| D | PO4400 |
Functional Information from PROSITE/UniProt
| site_id | PS00112 |
| Number of Residues | 7 |
| Details | PHOSPHAGEN_KINASE Phosphagen kinase active site signature. CP.SNLGT |
| Chain | Residue | Details |
| A | CYS278-THR284 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 344 |
| Details | Domain: {"description":"Phosphagen kinase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00842","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 968 |
| Details | Domain: {"description":"Phosphagen kinase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00843","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00843","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1bg0 |
| Chain | Residue | Details |
| A | ARG231 | |
| A | ARG287 | |
| A | ARG315 | |
| A | ARG127 | |
| A | GLU227 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1bg0 |
| Chain | Residue | Details |
| B | ARG231 | |
| B | ARG287 | |
| B | ARG315 | |
| B | ARG127 | |
| B | GLU227 |
| site_id | CSA3 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1bg0 |
| Chain | Residue | Details |
| C | ARG231 | |
| C | ARG287 | |
| C | ARG315 | |
| C | ARG127 | |
| C | GLU227 |
| site_id | CSA4 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1bg0 |
| Chain | Residue | Details |
| D | ARG231 | |
| D | ARG287 | |
| D | ARG315 | |
| D | ARG127 | |
| D | GLU227 |
