1CRG
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005739 | cellular_component | mitochondrion |
A | 0005758 | cellular_component | mitochondrial intermembrane space |
A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
A | 0009055 | molecular_function | electron transfer activity |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
A | 1901612 | molecular_function | cardiolipin binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 117 |
Chain | Residue |
A | GLY1 |
A | SER2 |
A | ALA3 |
A | LYS4 |
A | SER47 |
A | LYS73 |
site_id | AC2 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE HEC A 104 |
Chain | Residue |
A | HIS18 |
A | GLY23 |
A | VAL28 |
A | GLY29 |
A | LEU32 |
A | ILE35 |
A | SER40 |
A | GLY41 |
A | TYR46 |
A | TYR48 |
A | THR49 |
A | ILE52 |
A | TRP59 |
A | MET64 |
A | THR78 |
A | LYS79 |
A | MET80 |
A | LEU94 |
A | LEU98 |
A | ARG13 |
A | CYS14 |
A | CYS17 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: covalent => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
Chain | Residue | Details |
A | LEU15 | |
A | HIS18 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: axial binding residue => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
Chain | Residue | Details |
A | THR19 | |
A | ALA81 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: N6,N6,N6-trimethyllysine; by CTM1 => ECO:0000269|PubMed:10791961, ECO:0000269|PubMed:11880631, ECO:0007744|PDB:1KYO |
Chain | Residue | Details |
A | LYS73 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:10821864, ECO:0000269|PubMed:18390544 |
Chain | Residue | Details |
A | TYR74 |