Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE AG7 A 501 |
| Chain | Residue |
| A | PRO2 |
| A | ASN130 |
| A | THR142 |
| A | LYS143 |
| A | GLY145 |
| A | TYR146 |
| A | CYS147 |
| A | HIS161 |
| A | VAL162 |
| A | GLY163 |
| A | GLY164 |
| A | ASN22 |
| A | ASN165 |
| A | PHE170 |
| A | HOH739 |
| A | HOH823 |
| A | LYS24 |
| A | PHE25 |
| A | HIS40 |
| A | GLU71 |
| A | LEU126 |
| A | LEU127 |
| A | SER128 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 178 |
| Details | Domain: {"description":"Peptidase C3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For protease 3C activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10500114, 2158990, 7515772, 20107288, 9060667 |
| Chain | Residue | Details |
| A | CYS147 | |
| A | CYS147 | |
| A | HIS40 | |
| A | GLU71 | |
| A | GLY145 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 477 |
| Chain | Residue | Details |
| A | HIS40 | electrostatic stabiliser, proton shuttle (general acid/base) |
| A | GLU71 | electrostatic stabiliser, modifies pKa |
| A | GLY145 | electrostatic stabiliser |
| A | CYS147 | electrostatic stabiliser |
