Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE HEM A 430 |
Chain | Residue |
A | LEU102 |
A | VAL314 |
A | PHE317 |
A | ARG319 |
A | TYR342 |
A | GLY369 |
A | PHE370 |
A | GLY371 |
A | TRP372 |
A | HIS375 |
A | MET376 |
A | THR103 |
A | CYS377 |
A | GLY379 |
A | LEU382 |
A | MET387 |
A | HOH440 |
A | HOH522 |
A | HOH554 |
A | HOH590 |
A | HIS110 |
A | ARG114 |
A | ALA267 |
A | GLY268 |
A | THR271 |
A | SER275 |
A | PRO313 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGwGAHMCLG |
Chain | Residue | Details |
A | PHE370-GLY379 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: axial binding residue |
Chain | Residue | Details |
A | CYS377 | |