1CNN

OMEGA-CONOTOXIN MVIIC FROM CONUS MAGUS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005246	molecular_function	calcium channel regulator activity
A	0005576	cellular_component	extracellular region
A	0008200	molecular_function	ion channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0044231	cellular_component	host cell presynaptic membrane
A	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NH2 A 27

Chain	Residue
A	SER19
A	CYS26

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Functional Information from PROSITE/UniProt

site_id	PS60004
Number of Residues	26
Details	OMEGA_CONOTOXIN Omega-conotoxin family signature. CKgkGaPCRkt...MYdCCSg.SCgr.RGKC

Chain	Residue	Details
A	CYS1-CYS26

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Important for Cav2.1/CACNA1A calcium channel binding => ECO:0000305|PubMed:7677735

Chain	Residue	Details
A	TYR13

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Cysteine amide => ECO:0000269|PubMed:1352986

Chain	Residue	Details
A	CYS26

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