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1CMC

THREE DIMENSIONAL CRYSTAL STRUCTURES OF E. COLI MET REPRESSOR WITH AND WITHOUT COREPRESSOR

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006355biological_processregulation of DNA-templated transcription
A0006555biological_processmethionine metabolic process
A0008652biological_processamino acid biosynthetic process
A0009086biological_processmethionine biosynthetic process
A0045892biological_processnegative regulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006355biological_processregulation of DNA-templated transcription
B0006555biological_processmethionine metabolic process
B0008652biological_processamino acid biosynthetic process
B0009086biological_processmethionine biosynthetic process
B0045892biological_processnegative regulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 106
ChainResidue
AHIS14
AGLU19
AGLU103
ATYR104

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG B 106
ChainResidue
BHIS14
BGLU19
BGLU103
BTYR104

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE SAM A 105
ChainResidue
AHIS63
AALA64
APHE65
AHOH121
AHOH134
AHOH166
AHOH214
BGLU39
BARG43
BLEU56
BGLU59
BHIS63
BPRO71
APHE61

site_idAC4
Number of Residues14
DetailsBINDING SITE FOR RESIDUE SAM B 105
ChainResidue
AGLU39
AARG43
ALEU56
AGLU59
AALA60
AHIS63
APRO71
BPHE61
BHIS63
BALA64
BPHE65
BHOH145
BHOH160
BHOH162

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PDB entries from 2025-06-18

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