1CLI

X-RAY CRYSTAL STRUCTURE OF AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE (PURM), FROM THE E. COLI PURINE BIOSYNTHETIC PATHWAY, AT 2.5 A RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004637	molecular_function	phosphoribosylamine-glycine ligase activity
A	0004641	molecular_function	phosphoribosylformylglycinamidine cyclo-ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016874	molecular_function	ligase activity
A	0046084	biological_process	adenine biosynthetic process
B	0004637	molecular_function	phosphoribosylamine-glycine ligase activity
B	0004641	molecular_function	phosphoribosylformylglycinamidine cyclo-ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006189	biological_process	'de novo' IMP biosynthetic process
B	0016874	molecular_function	ligase activity
B	0046084	biological_process	adenine biosynthetic process
C	0004637	molecular_function	phosphoribosylamine-glycine ligase activity
C	0004641	molecular_function	phosphoribosylformylglycinamidine cyclo-ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006189	biological_process	'de novo' IMP biosynthetic process
C	0016874	molecular_function	ligase activity
C	0046084	biological_process	adenine biosynthetic process
D	0004637	molecular_function	phosphoribosylamine-glycine ligase activity
D	0004641	molecular_function	phosphoribosylformylglycinamidine cyclo-ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006189	biological_process	'de novo' IMP biosynthetic process
D	0016874	molecular_function	ligase activity
D	0046084	biological_process	adenine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 4350

Chain	Residue
A	THR69
A	ASN192
A	GLY193
A	TYR194
A	SER195
A	HOH4420

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 1350

Chain	Residue
B	GLY1193
B	TYR1194
B	SER1195
B	GLY1068
B	THR1069
B	ASN1192

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 2350

Chain	Residue
C	THR2069
C	ASN2192
C	GLY2193
C	TYR2194
C	SER2195

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 3350

Chain	Residue
D	GLY3068
D	THR3069
D	ASN3192
D	GLY3193
D	TYR3194
D	SER3195

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