Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009715 | biological_process | chalcone biosynthetic process |
| A | 0009813 | biological_process | flavonoid biosynthetic process |
| A | 0016210 | molecular_function | naringenin-chalcone synthase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0030639 | biological_process | polyketide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE STL A 390 |
| Chain | Residue |
| A | ASP255 |
| A | GLY256 |
| A | THR264 |
| A | PHE265 |
| A | ASN336 |
| A | SER338 |
| A | PRO375 |
| A | HOH458 |
| A | HOH694 |
| A | HOH722 |
| A | GLU192 |
| A | VAL193 |
| A | THR194 |
| A | THR197 |
| A | PHE215 |
| A | GLY216 |
| A | ASP217 |
| A | ILE254 |
| site_id | CYS |
| Number of Residues | 1 |
| Details | CATALYTIC SITE |
Functional Information from PROSITE/UniProt
| site_id | PS00441 |
| Number of Residues | 17 |
| Details | CHALCONE_SYNTH Chalcone and stilbene synthases active site. RYmMyQqGCFAGGTvLR |
| Chain | Residue | Details |
| A | ARG156-ARG172 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Acyl-thioester intermediate","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10426957","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10426957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10653632","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1cgk |
| Chain | Residue | Details |
| A | PHE215 | |
| A | CYS164 | |
| A | ASN336 | |
| A | HIS303 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 355 |
| Chain | Residue | Details |
| A | CYS164 | activator, covalently attached, nucleofuge, nucleophile |
| A | PHE215 | electrostatic destabiliser, polar/non-polar interaction |
| A | HIS303 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN336 | electrostatic stabiliser, hydrogen bond donor |
1CGZ
