Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004645 | molecular_function | 1,4-alpha-oligoglucan phosphorylase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006738 | biological_process | nicotinamide riboside catabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0017061 | molecular_function | S-methyl-5-thioadenosine phosphorylase activity |
| A | 0033353 | biological_process | L-methionine cycle |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 295 |
| Chain | Residue |
| A | GLY17 |
| A | THR18 |
| A | ARG60 |
| A | HIS61 |
| A | THR93 |
| A | ALA94 |
| A | THR197 |
| A | MTA292 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MTA A 292 |
| Chain | Residue |
| A | CYS95 |
| A | GLY96 |
| A | PHE177 |
| A | ASN195 |
| A | MET196 |
| A | THR219 |
| A | ASP220 |
| A | ASP222 |
| A | SO4295 |
| A | HOH305 |
| A | ALA94 |
Functional Information from PROSITE/UniProt
| site_id | PS01240 |
| Number of Residues | 41 |
| Details | PNP_MTAP_2 Purine and other phosphorylases family 2 signature. LarhGrqHtImpskVnyqAn.IwAlkeeGcth.VIvtTAcGSL |
| Chain | Residue | Details |
| A | LEU58-LEU98 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"10404592","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CG6","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15122881","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K27","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10404592","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CB0","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for substrate specificity","evidences":[{"source":"PubMed","id":"10404592","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CQ65","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 10404592 |
| Chain | Residue | Details |
| A | ASP220 | |
| A | ASP222 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 244 |
| Chain | Residue | Details |
| A | ASP220 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP222 | electrostatic stabiliser |
1CG6
