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1CEW

THE 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF CHICKEN EGG WHITE CYSTATIN AND ITS POSSIBLE MODE OF INTERACTION WITH CYSTEINE PROTEINASES

Functional Information from GO Data
ChainGOidnamespacecontents
I0004869molecular_functioncysteine-type endopeptidase inhibitor activity
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005737cellular_componentcytoplasm
I0030414molecular_functionpeptidase inhibitor activity
I0031982cellular_componentvesicle
Functional Information from PROSITE/UniProt
site_idPS00287
Number of Residues14
DetailsCYSTATIN Cysteine proteases inhibitors signature. RQLVSGIKYiLQVE
ChainResidueDetails
IARG52-GLU65

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMotif: {"description":"Secondary area of contact"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsSite: {"description":"Reactive site"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"2721673","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

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PDB entries from 2025-12-03

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