Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| B | 0046656 | biological_process | folic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG85 |
| A | ARG88 |
| A | TRP89 |
| A | ARG92 |
| A | HOH713 |
| A | HOH716 |
| A | HOH738 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | TRP89 |
| B | ARG92 |
| B | HOH618 |
| B | HOH628 |
| B | HOH631 |
| B | HOH732 |
| B | ARG85 |
| B | ARG88 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ROI A 601 |
| Chain | Residue |
| A | SER43 |
| A | LYS44 |
| A | LEU46 |
| A | TYR54 |
| A | ASN56 |
| A | TRP89 |
| A | ARG92 |
| A | ASP95 |
| A | PHE123 |
| A | HOH683 |
| A | HOH713 |
| A | HOH743 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ROI B 602 |
| Chain | Residue |
| B | SER43 |
| B | LYS44 |
| B | LEU46 |
| B | TYR54 |
| B | ASN56 |
| B | TRP89 |
| B | ARG92 |
| B | ASP95 |
| B | PHE123 |
| B | HOH624 |
| B | HOH631 |
Functional Information from PROSITE/UniProt
| site_id | PS00794 |
| Number of Residues | 12 |
| Details | HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. RwGERtlDLDIL |
| Chain | Residue | Details |
| A | ARG88-LEU99 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hka |
| Chain | Residue | Details |
| A | ARG83 | |
| A | ARG92 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hka |
| Chain | Residue | Details |
| B | ARG83 | |
| B | ARG92 | |
