1C6W

MAUROCALCIN FROM SCORPIO MAURUS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005246	molecular_function	calcium channel regulator activity
A	0005576	cellular_component	extracellular region
A	0019855	molecular_function	calcium channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS60028
Number of Residues	30
Details	SCORPION_CALCINE Scorpion calcine family signature. ClphlklCkenkdCCskkCkrrgtniekRC

Chain	Residue	Details
A	CYS3-CYS32

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Important for stimulation of [3H]ryanodine binding to RYR => ECO:0000269|PubMed:12869557, ECO:0000269|PubMed:17888395

Chain	Residue	Details
A	LYS8

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Mildly important for stimulation of [3H]ryanodine binding to RYR => ECO:0000269|PubMed:12869557, ECO:0000269|PubMed:17888395

Chain	Residue	Details
A	LYS19
A	LYS20
A	THR26

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Essential for stimulation of [3H]ryanodine binding to RYR1 => ECO:0000250|UniProtKB:P59868

Chain	Residue	Details
A	ARG31
A	ARG33

---