1C6W
MAUROCALCIN FROM SCORPIO MAURUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005246 | molecular_function | calcium channel regulator activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0019855 | molecular_function | calcium channel inhibitor activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PROSITE/UniProt
| site_id | PS60028 |
| Number of Residues | 30 |
| Details | SCORPION_CALCINE Scorpion calcine family signature. ClphlklCkenkdCCskkCkrrgtniekRC |
| Chain | Residue | Details |
| A | CYS3-CYS32 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Peptide: {"description":"Maurocalcin","featureId":"PRO_0000044950","evidences":[{"source":"PubMed","id":"10713267","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Region: {"description":"Essential for stimulation of [3H]ryanodine binding to RYR","evidences":[{"source":"PubMed","id":"12869557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17888395","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for stimulation of [3H]ryanodine binding to RYR","evidences":[{"source":"PubMed","id":"12869557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17888395","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Site: {"description":"Mildly important for stimulation of [3H]ryanodine binding to RYR","evidences":[{"source":"PubMed","id":"12869557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17888395","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for stimulation of [3H]ryanodine binding to RYR1","evidences":[{"source":"UniProtKB","id":"P59868","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
