1C3Q
CRYSTAL STRUCTURE OF NATIVE THIAZOLE KINASE IN THE MONOCLINIC FORM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004417 | molecular_function | hydroxyethylthiazole kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | ASN26 |
| B | ASN26 |
| C | ASN26 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TZE A 301 |
| Chain | Residue |
| C | THR194 |
| C | GLY195 |
| C | CYS198 |
| A | PRO43 |
| A | VAL44 |
| A | MET45 |
| A | HOH371 |
| C | ASN25 |
| C | GLY67 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TZE A 302 |
| Chain | Residue |
| A | ASN25 |
| A | GLY67 |
| A | GLY195 |
| A | CYS198 |
| A | HOH352 |
| A | HOH365 |
| B | PRO43 |
| B | VAL44 |
| B | MET45 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TZE B 303 |
| Chain | Residue |
| B | ASN25 |
| B | GLY67 |
| B | THR194 |
| B | GLY195 |
| B | HOH341 |
| C | MET45 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00228","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10891066","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
