1C2U
SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0015459 | molecular_function | potassium channel regulator activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0042151 | cellular_component | nematocyst |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | SITE: Important residue for binding Kv1.3/KCNA3 => ECO:0000269|PubMed:26288216 |
| Chain | Residue | Details |
| A | ILE7 | |
| A | SER20 | |
| A | ALA21 | |
| A | TYR23 | |
| A | PHE27 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Important residue for binding Kv1.3/KCNA3 => ECO:0000269|PubMed:8645244 |
| Chain | Residue | Details |
| A | LYS9 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Important residue for binding Kv1.3/KCNA3 => ECO:0000269|PubMed:26288216, ECO:0000269|PubMed:8645244 |
| Chain | Residue | Details |
| A | ARG11 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Key residue for binding both Kv1.2/KCNA2 and Kv1.3/KCNA3 (occludes the channel pore like a cork in a bottle) => ECO:0000269|PubMed:26288216, ECO:0000269|PubMed:8645244 |
| Chain | Residue | Details |
| A | LYS22 |
