Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1C17

A1C12 SUBCOMPLEX OF F1FO ATP SYNTHASE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0008289	molecular_function	lipid binding
A	0015078	molecular_function	proton transmembrane transporter activity
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
A	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0008289	molecular_function	lipid binding
B	0015078	molecular_function	proton transmembrane transporter activity
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
B	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0008289	molecular_function	lipid binding
C	0015078	molecular_function	proton transmembrane transporter activity
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
C	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006754	biological_process	ATP biosynthetic process
D	0008289	molecular_function	lipid binding
D	0015078	molecular_function	proton transmembrane transporter activity
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
D	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0006754	biological_process	ATP biosynthetic process
E	0008289	molecular_function	lipid binding
E	0015078	molecular_function	proton transmembrane transporter activity
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
E	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0006754	biological_process	ATP biosynthetic process
F	0008289	molecular_function	lipid binding
F	0015078	molecular_function	proton transmembrane transporter activity
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
F	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0006754	biological_process	ATP biosynthetic process
G	0008289	molecular_function	lipid binding
G	0015078	molecular_function	proton transmembrane transporter activity
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0006754	biological_process	ATP biosynthetic process
H	0008289	molecular_function	lipid binding
H	0015078	molecular_function	proton transmembrane transporter activity
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
H	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005886	cellular_component	plasma membrane
I	0006754	biological_process	ATP biosynthetic process
I	0008289	molecular_function	lipid binding
I	0015078	molecular_function	proton transmembrane transporter activity
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
I	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005886	cellular_component	plasma membrane
J	0006754	biological_process	ATP biosynthetic process
J	0008289	molecular_function	lipid binding
J	0015078	molecular_function	proton transmembrane transporter activity
J	0015986	biological_process	proton motive force-driven ATP synthesis
J	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
J	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
J	0045259	cellular_component	proton-transporting ATP synthase complex
J	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
J	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport
K	0005886	cellular_component	plasma membrane
K	0006754	biological_process	ATP biosynthetic process
K	0008289	molecular_function	lipid binding
K	0015078	molecular_function	proton transmembrane transporter activity
K	0015986	biological_process	proton motive force-driven ATP synthesis
K	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
K	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
K	0045259	cellular_component	proton-transporting ATP synthase complex
K	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
K	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	1902600	biological_process	proton transmembrane transport
L	0005886	cellular_component	plasma membrane
L	0006754	biological_process	ATP biosynthetic process
L	0008289	molecular_function	lipid binding
L	0015078	molecular_function	proton transmembrane transporter activity
L	0015986	biological_process	proton motive force-driven ATP synthesis
L	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
L	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
L	0045259	cellular_component	proton-transporting ATP synthase complex
L	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	1902600	biological_process	proton transmembrane transport
M	0015078	molecular_function	proton transmembrane transporter activity
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)

Functional Information from PROSITE/UniProt

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. SLGLRLFGNM

Chain	Residue	Details
M	SER206-MET215

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. ARQPdliplLrTqfFIvmgLvD

Chain	Residue	Details
A	ALA40-ASP61

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	TRANSMEM: Helical => ECO:0000305

Chain	Residue	Details
M	LEU100-LEU120
E	VAL74-ALA79
F	MET1-TYR10
F	VAL74-ALA79
G	MET1-TYR10
G	VAL74-ALA79
H	MET1-TYR10
H	VAL74-ALA79
I	MET1-TYR10
I	VAL74-ALA79
J	MET1-TYR10
M	ASP146-ILE166
J	VAL74-ALA79
K	MET1-TYR10
K	VAL74-ALA79
L	MET1-TYR10
L	VAL74-ALA79
M	LEU220-PRO240
M	ALA242-VAL262
C	MET1-TYR10
C	VAL74-ALA79
D	MET1-TYR10
D	VAL74-ALA79
E	MET1-TYR10

site_id	SWS_FT_FI2
Number of Residues	25
Details	TOPO_DOM: Periplasmic => ECO:0000305

Chain	Residue	Details
M	LEU121-ALA145
E	PHE53-TYR73
F	MET11-LEU31
F	PHE53-TYR73
G	MET11-LEU31
G	PHE53-TYR73
H	MET11-LEU31
H	PHE53-TYR73
I	MET11-LEU31
I	PHE53-TYR73
J	MET11-LEU31
M	TRP241
J	PHE53-TYR73
K	MET11-LEU31
K	PHE53-TYR73
L	MET11-LEU31
L	PHE53-TYR73
B	MET11-LEU31
B	PHE53-TYR73
C	MET11-LEU31
C	PHE53-TYR73
D	MET11-LEU31
D	PHE53-TYR73
E	MET11-LEU31

site_id	SWS_FT_FI3
Number of Residues	60
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
M	LYS167-GLU219
J	GLY32-GLN52
K	GLY32-GLN52
L	GLY32-GLN52
M	TYR263-HIS271
C	GLY32-GLN52
D	GLY32-GLN52
E	GLY32-GLN52
F	GLY32-GLN52
G	GLY32-GLN52
H	GLY32-GLN52
I	GLY32-GLN52

site_id	SWS_FT_FI4
Number of Residues	12
Details	SITE: Reversibly protonated during proton transport

Chain	Residue	Details
A	ASP61
J	ASP61
K	ASP61
L	ASP61
B	ASP61
C	ASP61
D	ASP61
E	ASP61
F	ASP61
G	ASP61
H	ASP61
I	ASP61

site_id	SWS_FT_FI5
Number of Residues	12
Details	MOD_RES: N-formylmethionine => ECO:0000250

Chain	Residue	Details
A	MET1
J	MET1
K	MET1
L	MET1
B	MET1
C	MET1
D	MET1
E	MET1
F	MET1
G	MET1
H	MET1
I	MET1

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
A	ASP61
M	SER206
M	ASN214
M	ARG210

site_id	CSA10
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
J	ASP61

site_id	CSA11
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
K	ASP61

site_id	CSA12
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
L	ASP61

site_id	CSA2
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
B	ASP61

site_id	CSA3
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
C	ASP61

site_id	CSA4
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
D	ASP61

site_id	CSA5
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
E	ASP61

site_id	CSA6
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
F	ASP61

site_id	CSA7
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
G	ASP61

site_id	CSA8
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
H	ASP61

site_id	CSA9
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 8399181, 11969414, 10580496, 9405480, 14990464

Chain	Residue	Details
I	ASP61

site_id	MCSA1
Number of Residues	3
Details	M-CSA 507

Chain	Residue	Details
M	SER206	proton acceptor, proton donor, proton relay
M	ARG210	electrostatic stabiliser
M	ASN214	proton acceptor

site_id	MCSA10
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
J	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA11
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
K	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA12
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
L	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA2
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
B	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA3
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
C	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA4
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
D	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA5
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
E	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA6
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
F	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA7
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
G	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA8
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
H	ASP61	electrostatic stabiliser, proton acceptor, proton donor

site_id	MCSA9
Number of Residues	1
Details	M-CSA 507

Chain	Residue	Details
I	ASP61	electrostatic stabiliser, proton acceptor, proton donor

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)