Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1C0U

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+50.0934

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0003964molecular_functionRNA-directed DNA polymerase activity
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
A0006278biological_processRNA-templated DNA biosynthetic process
B0003964molecular_functionRNA-directed DNA polymerase activity
B0006278biological_processRNA-templated DNA biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE BM5 A 999
ChainResidue
ALEU100
ATRP229
ATYR318
BGLU138
ALYS101
ALYS103
AVAL106
AVAL179
AILE180
ATYR181
ATYR188
AGLY190

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BVAL111
BASP186
BLEU187

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Cleavage; by viral protease => ECO:0000250
ChainResidueDetails
BPRO1
ASER499

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Essential for RT p66/p51 heterodimerization => ECO:0000250
ChainResidueDetails
BTRP402
BGLU415

site_idSWS_FT_FI4
Number of Residues1
DetailsSITE: Cleavage; by viral protease => ECO:0000250
ChainResidueDetails
APRO1

site_idSWS_FT_FI5
Number of Residues2
DetailsSITE: Essential for RT p66/p51 heterodimerization => ECO:0000250
ChainResidueDetails
ATRP402
AGLU415

site_idSWS_FT_FI6
Number of Residues1
DetailsSITE: Cleavage; by viral protease; partial => ECO:0000250
ChainResidueDetails
ATYR441

Catalytic Information from CSA
site_idMCSA1
Number of Residues
DetailsM-CSA 175
ChainResidueDetails

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon