1BY5
FHUA FROM E. COLI, WITH ITS LIGAND FERRICHROME
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| A | 0015344 | molecular_function | siderophore uptake transmembrane transporter activity |
| A | 0015643 | molecular_function | toxic substance binding |
| A | 0015891 | biological_process | siderophore transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019904 | molecular_function | protein domain specific binding |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0044718 | biological_process | siderophore transmembrane transport |
| A | 0046790 | molecular_function | virion binding |
| A | 1902495 | cellular_component | transmembrane transporter complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FE B 800 |
| Chain | Residue |
| B | AHO801 |
| B | AHO802 |
| B | AHO803 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE OES A 715 |
| Chain | Residue |
| A | THR176 |
| A | SER200 |
| A | GLN211 |
| A | TYR213 |
| A | PHE290 |
| A | LEU361 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OES A 716 |
| Chain | Residue |
| A | GLY169 |
| A | TRP221 |
| A | OES719 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE OES A 717 |
| Chain | Residue |
| A | PHE180 |
| A | THR432 |
| A | VAL434 |
| A | TRP455 |
| A | PHE714 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE OES A 718 |
| Chain | Residue |
| A | PHE294 |
| A | OES722 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OES A 719 |
| Chain | Residue |
| A | PHE166 |
| A | LYS167 |
| A | ALA168 |
| A | TYR284 |
| A | VAL296 |
| A | GLN298 |
| A | VAL676 |
| A | ALA708 |
| A | ALA710 |
| A | OES716 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OES A 720 |
| Chain | Residue |
| A | PHE302 |
| A | GLU304 |
| A | GLN353 |
| A | TYR664 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE OES A 721 |
| Chain | Residue |
| A | PHE180 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE OES A 722 |
| Chain | Residue |
| A | ASN237 |
| A | OES718 |
Functional Information from PROSITE/UniProt
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. GcfwGaERqVvATAtFrF |
| Chain | Residue | Details |
| A | GLY697-PHE714 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 177 |
| Details | Transmembrane: {"description":"Beta stranded"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 289 |
| Details | Topological domain: {"description":"Extracellular"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Topological domain: {"description":"Periplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 112 |
| Details | Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 555 |
| Details | Domain: {"description":"TBDR beta-barrel","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 17 |
| Details | Motif: {"description":"TonB C-terminal box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10850805","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9865695","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with phage T5 RBP-pb5","evidences":[{"source":"PubMed","id":"36779755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
