1BWR
PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003847 | molecular_function | 1-alkyl-2-acetylglycerophosphocholine esterase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006629 | biological_process | lipid metabolic process |
A | 0007283 | biological_process | spermatogenesis |
A | 0008247 | cellular_component | 1-alkyl-2-acetylglycerophosphocholine esterase complex |
A | 0016042 | biological_process | lipid catabolic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0042802 | molecular_function | identical protein binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0046982 | molecular_function | protein heterodimerization activity |
A | 0047179 | molecular_function | platelet-activating factor acetyltransferase activity |
Functional Information from PDB Data
site_id | ZNB |
Number of Residues | 3 |
Details | ACTIVE SITE |
Chain | Residue |
A | SER47 |
A | ASP192 |
A | HIS195 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:8985254, ECO:0007744|PDB:1BWP |
Chain | Residue | Details |
A | SER47 | |
A | ASP192 | |
A | HIS195 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q15102 |
Chain | Residue | Details |
A | SER2 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 94 |
Chain | Residue | Details |
A | SER47 | covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
A | GLY74 | electrostatic stabiliser, hydrogen bond donor |
A | ASN104 | electrostatic stabiliser, hydrogen bond donor |
A | ASP192 | activator, electrostatic stabiliser, hydrogen bond acceptor |
A | HIS195 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |