Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 0ZY A 732 |
| Chain | Residue |
| A | PHE41 |
| A | HIS57 |
| A | LEU99 |
| A | GLN175 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | SER202 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | SER217 |
| A | HOH256 |
| A | HOH274 |
| A | HOH288 |
| A | HOH365 |
| A | HOH451 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 247 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH269 |
| A | HOH291 |
| site_id | BIN |
| Number of Residues | 10 |
| Details | SUBSTRATE BINDING SITE |
| Chain | Residue |
| A | GLY216 |
| A | SER217 |
| A | GLY219 |
| A | CYS220 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | SER214 |
| A | TRP215 |
| site_id | CAT |
| Number of Residues | 3 |
| Details | ACTIVE SITE, CATALYTIC TRIAD |
| Chain | Residue |
| A | HIS57 |
| A | ASP189 |
| A | SER195 |
| site_id | ION |
| Number of Residues | 11 |
| Details | CALCIUM BINDING SITE |
| Chain | Residue |
| A | GLU70 |
| A | ASP71 |
| A | ASN72 |
| A | ILE73 |
| A | ASN74 |
| A | VAL75 |
| A | VAL76 |
| A | GLU77 |
| A | GLY78 |
| A | ASN79 |
| A | GLU80 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | LYS60 | |
| A | LEU105 | |
| A | PRO198 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ILE73 | |
| A | VAL75 | |
| A | GLY78 | |
| A | ILE83 | |
| A | GLN192 | |
| A | SER195 | |
| A | PRO198 | |
