1BT3

CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE NATIVE CU(II)-CU(II) STATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004097	molecular_function	catechol oxidase activity
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE C2O A 500

Chain	Residue
A	HIS240
A	HIS244
A	HIS274
A	HIS88
A	HIS109
A	HIS118

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site_id	CUA
Number of Residues	3
Details	BINDING SITE FOR COPPER A

Chain	Residue
A	HIS88
A	HIS109
A	HIS118

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site_id	CUB
Number of Residues	3
Details	BINDING SITE FOR COPPER B

Chain	Residue
A	HIS240
A	HIS244
A	HIS274

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Functional Information from PROSITE/UniProt

site_id	PS00497
Number of Residues	18
Details	TYROSINASE_1 Tyrosinase CuA-binding region signature. Hnswl.FFpFHRwyLyfyE

Chain	Residue	Details
A	HIS109-GLU126

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9846879","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"2'-(S-cysteinyl)-histidine (Cys-His)","evidences":[{"source":"PubMed","id":"9846879","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1bt1

Chain	Residue	Details
A	GLU236

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site_id	MCSA1
Number of Residues	7
Details	M-CSA 125

Chain	Residue	Details
A	HIS88	metal ligand
A	HIS109	metal ligand
A	HIS118	metal ligand
A	HIS240	metal ligand
A	HIS244	metal ligand
A	PHE261	polar/non-polar interaction, steric role
A	HIS274	metal ligand

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