Functional Information from GO Data
| Chain | GOid | namespace | contents |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0005509 | molecular_function | calcium ion binding |
| E | 0005515 | molecular_function | protein binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005615 | cellular_component | extracellular space |
| E | 0006508 | biological_process | proteolysis |
| E | 0007584 | biological_process | response to nutrient |
| E | 0007586 | biological_process | digestion |
| E | 0008236 | molecular_function | serine-type peptidase activity |
| E | 0030574 | biological_process | collagen catabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | CAT |
| Number of Residues | 3 |
| Details | CATALYTIC TRIAD RESIDUES, CONSERVED IN ALL SERINE PROTEASES OF THE TRYPSIN AND SUBTILISIN STRUCTURAL CLASSES |
| Chain | Residue |
| E | HIS57 |
| E | ASP102 |
| E | SER195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| E | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. GScqGDSGGPVV |
| Chain | Residue | Details |
| E | GLY189-VAL200 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FfyGGCggnrnnFdteeyC |
| Chain | Residue | Details |
| I | PHE33-CYS51 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Reactive bond |
| Chain | Residue | Details |
| I | ARG15 | |
| E | ASP102 | |
| E | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Sulfotyrosine => ECO:0000255 |
| Chain | Residue | Details |
| I | TYR50 | |
| E | ASN72 | |
| E | VAL75 | |
| E | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| E | GLY189 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | HIS57 | |
| E | GLY196 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | ASP102 | |
| E | SER195 | |
| E | GLY193 | |
| E | HIS57 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY193 | |
| E | ASP95 | |
| E | HIS57 | |
