Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1BR2

SMOOTH MUSCLE MYOSIN MOTOR DOMAIN COMPLEXED WITH MGADP.ALF4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003774	molecular_function	cytoskeletal motor activity
A	0005524	molecular_function	ATP binding
A	0016459	cellular_component	myosin complex
A	0051015	molecular_function	actin filament binding
B	0003774	molecular_function	cytoskeletal motor activity
B	0005524	molecular_function	ATP binding
B	0016459	cellular_component	myosin complex
B	0051015	molecular_function	actin filament binding
C	0003774	molecular_function	cytoskeletal motor activity
C	0005524	molecular_function	ATP binding
C	0016459	cellular_component	myosin complex
C	0051015	molecular_function	actin filament binding
D	0003774	molecular_function	cytoskeletal motor activity
D	0005524	molecular_function	ATP binding
D	0016459	cellular_component	myosin complex
D	0051015	molecular_function	actin filament binding
E	0003774	molecular_function	cytoskeletal motor activity
E	0005524	molecular_function	ATP binding
E	0016459	cellular_component	myosin complex
E	0051015	molecular_function	actin filament binding
F	0003774	molecular_function	cytoskeletal motor activity
F	0005524	molecular_function	ATP binding
F	0016459	cellular_component	myosin complex
F	0051015	molecular_function	actin filament binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 997

Chain	Residue
A	THR184
A	SER246
A	ASP465
A	HOH995
A	ADP998
A	ALF999

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ALF A 999

Chain	Residue
A	SER246
A	ASP465
A	ILE466
A	GLY468
A	HOH995
A	MG997
A	ADP998
A	SER179
A	LYS183
A	SER245

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 997

Chain	Residue
B	THR184
B	SER246
B	ASP465
B	HOH995
B	ADP998
B	ALF999

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF B 999

Chain	Residue
B	SER179
B	LYS183
B	SER245
B	SER246
B	ASP465
B	ILE466
B	ALA467
B	GLY468
B	HOH995
B	MG997
B	ADP998

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 997

Chain	Residue
C	THR184
C	SER246
C	ASP465
C	HOH995
C	ADP998
C	ALF999

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ALF C 999

Chain	Residue
C	SER179
C	LYS183
C	ASN242
C	SER245
C	SER246
C	ASP465
C	GLY468
C	HOH995
C	MG997
C	ADP998

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 997

Chain	Residue
D	THR184
D	SER246
D	ASP465
D	HOH995
D	ADP998
D	ALF999

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF D 999

Chain	Residue
D	SER179
D	LYS183
D	SER245
D	SER246
D	ASP465
D	ILE466
D	ALA467
D	GLY468
D	HOH995
D	MG997
D	ADP998

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 997

Chain	Residue
E	THR184
E	SER246
E	ASP465
E	HOH995
E	ADP998
E	ALF999

site_id	BC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF E 999

Chain	Residue
E	SER179
E	LYS183
E	SER245
E	SER246
E	ASP465
E	ILE466
E	ALA467
E	GLY468
E	HOH995
E	MG997
E	ADP998

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 997

Chain	Residue
F	THR184
F	SER246
F	ASP465
F	HOH995
F	ADP998
F	ALF999

site_id	BC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ALF F 999

Chain	Residue
F	SER179
F	LYS183
F	SER245
F	SER246
F	ILE466
F	ALA467
F	GLY468
F	HOH995
F	MG997
F	ADP998

site_id	BC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 998

Chain	Residue
A	ILE113
A	ASN125
A	PRO126
A	TYR127
A	LYS128
A	TYR133
A	GLY180
A	GLY182
A	LYS183
A	THR184
A	GLU185
A	ASN242
A	HOH995
A	HOH996
A	MG997
A	ALF999

site_id	BC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ADP B 998

Chain	Residue
B	ILE113
B	ASN125
B	PRO126
B	TYR127
B	TYR133
B	GLY180
B	GLY182
B	LYS183
B	THR184
B	GLU185
B	ASN242
B	HOH995
B	HOH996
B	MG997
B	ALF999

site_id	BC6
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP C 998

Chain	Residue
C	ILE113
C	ASN125
C	PRO126
C	TYR127
C	LYS128
C	TYR133
C	GLY180
C	GLY182
C	LYS183
C	THR184
C	GLU185
C	ASN242
C	HOH995
C	HOH996
C	MG997
C	ALF999

site_id	BC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ADP D 998

Chain	Residue
D	ILE113
D	ASN125
D	PRO126
D	TYR127
D	TYR133
D	GLY180
D	GLY182
D	LYS183
D	THR184
D	GLU185
D	ASN242
D	HOH995
D	HOH996
D	MG997
D	ALF999

site_id	BC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP E 998

Chain	Residue
E	ILE113
E	ASN125
E	PRO126
E	TYR127
E	LYS128
E	TYR133
E	GLY180
E	GLY182
E	LYS183
E	THR184
E	GLU185
E	ASN242
E	HOH995
E	HOH996
E	MG997
E	ALF999

site_id	BC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP F 998

Chain	Residue
F	ILE113
F	ASN125
F	PRO126
F	TYR127
F	LYS128
F	TYR133
F	GLY180
F	GLY182
F	LYS183
F	THR184
F	GLU185
F	ASN242
F	HOH995
F	HOH996
F	MG997
F	ALF999

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	Region: {"description":"Actin-binding"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	42
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	6
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"3312184","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
A	ASN242
A	GLY180
A	GLY468
A	GLU470

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
B	ASN242
B	GLY180
B	GLY468
B	GLU470

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
C	ASN242
C	GLY180
C	GLY468
C	GLU470

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
D	ASN242
D	GLY180
D	GLY468
D	GLU470

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
E	ASN242
E	GLY180
E	GLY468
E	GLU470

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1vom

Chain	Residue	Details
F	ASN242
F	GLY180
F	GLY468
F	GLU470

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)