1BIK
X-RAY STRUCTURE OF BIKUNIN FROM THE HUMAN INTER-ALPHA-INHIBITOR COMPLEX
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FqyGGCmgngnnFvtekeC |
| Chain | Residue | Details |
| A | PHE54-CYS72 | |
| A | PHE110-CYS128 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Inhibitory (P1) (chymotrypsin, elastase) => ECO:0000250 |
| Chain | Residue | Details |
| A | MET36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Inhibitory (P1) (trypsin) => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG92 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (Xyl...) (chondroitin sulfate) serine => ECO:0000269|PubMed:1898736, ECO:0000269|PubMed:25326458, ECO:0000269|PubMed:32337544, ECO:0000269|PubMed:36213313, ECO:0000269|PubMed:37453717, ECO:0000269|PubMed:6171497, ECO:0000269|PubMed:7682553 |
| Chain | Residue | Details |
| A | SER10 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:6171497 |
| Chain | Residue | Details |
| A | ASN45 |
