Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000976 | molecular_function | transcription cis-regulatory region binding |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003677 | molecular_function | DNA binding |
A | 0004077 | molecular_function | biotin-[acetyl-CoA-carboxylase] ligase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0006768 | biological_process | biotin metabolic process |
A | 0009102 | biological_process | biotin biosynthetic process |
A | 0009374 | molecular_function | biotin binding |
A | 0016874 | molecular_function | ligase activity |
A | 0017053 | cellular_component | transcription repressor complex |
A | 0036211 | biological_process | protein modification process |
A | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE BTN A 500 |
Chain | Residue |
A | SER89 |
A | THR90 |
A | ASN91 |
A | GLN112 |
A | GLY115 |
A | ARG116 |
A | TYR132 |
A | SER134 |
A | LYS183 |
A | GLY186 |
A | ILE187 |
A | GLY204 |
A | ALA205 |
site_id | CAT |
Number of Residues | 14 |
Details | |
Chain | Residue |
A | SER89 |
A | THR90 |
A | ASN91 |
A | GLN112 |
A | GLY115 |
A | ARG116 |
A | GLY117 |
A | ARG118 |
A | TYR132 |
A | LYS183 |
A | ILE187 |
A | LEU188 |
A | GLY204 |
A | ALA205 |
site_id | HTH |
Number of Residues | 25 |
Details | |
Chain | Residue |
A | GLY22 |
A | MET31 |
A | SER32 |
A | ARG33 |
A | ALA34 |
A | ALA35 |
A | ILE36 |
A | ASN37 |
A | LYS38 |
A | HIS39 |
A | ILE40 |
A | GLU23 |
A | GLN41 |
A | THR42 |
A | LEU43 |
A | ARG44 |
A | ASP45 |
A | TRP46 |
A | GLN24 |
A | LEU25 |
A | GLY26 |
A | GLU27 |
A | THR28 |
A | LEU29 |
A | GLY30 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLY22-GLN41 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | SER89 | |
A | ARG116 | |
Chain | Residue | Details |
A | GLN112 | |
A | LYS183 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | a catalytic site defined by CSA, PubMed 1409631 |
Chain | Residue | Details |
A | ARG118 | |
A | ARG317 | |
A | LYS183 | |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 538 |
Chain | Residue | Details |
A | ARG118 | electrostatic stabiliser |
A | LYS183 | electrostatic stabiliser |
A | ARG317 | |