1BI5

CHALCONE SYNTHASE FROM ALFALFA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009058	biological_process	biosynthetic process
A	0009715	biological_process	chalcone biosynthetic process
A	0009813	biological_process	flavonoid biosynthetic process
A	0016210	molecular_function	naringenin-chalcone synthase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0030639	biological_process	polyketide biosynthetic process

Functional Information from PDB Data

site_id	CYS
Number of Residues	1
Details	CATALYTIC SITE.

Chain	Residue
A	CSD164

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Functional Information from PROSITE/UniProt

site_id	PS00441
Number of Residues	17
Details	CHALCONE_SYNTH Chalcone and stilbene synthases active site. RYmMyQqGCFAGGTvLR

Chain	Residue	Details
A	ARG156-ARG172

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Acyl-thioester intermediate","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10426957","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10426957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10653632","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
A	PHE215
A	ASN336
A	HIS303

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site_id	MCSA1
Number of Residues	4
Details	M-CSA 355

Chain	Residue	Details
A	PHE165	activator, covalently attached, nucleofuge, nucleophile
A	ALA219	electrostatic destabiliser, polar/non-polar interaction
A	PRO307	electrostatic stabiliser, hydrogen bond donor
A	ALA340	electrostatic stabiliser, hydrogen bond donor

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