1BGY

CYTOCHROME BC1 COMPLEX FROM BOVINE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0046872	molecular_function	metal ion binding
A	0070469	cellular_component	respirasome
B	0004222	molecular_function	metalloendopeptidase activity
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006508	biological_process	proteolysis
B	0046872	molecular_function	metal ion binding
B	0070469	cellular_component	respirasome
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005750	cellular_component	mitochondrial respiratory chain complex III
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0022904	biological_process	respiratory electron transport chain
C	0031966	cellular_component	mitochondrial membrane
C	0045275	cellular_component	respiratory chain complex III
C	0046872	molecular_function	metal ion binding
C	0048039	molecular_function	ubiquinone binding
C	0070469	cellular_component	respirasome
C	1902600	biological_process	proton transmembrane transport
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
E	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
E	0016020	cellular_component	membrane
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005750	cellular_component	mitochondrial respiratory chain complex III
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0070469	cellular_component	respirasome
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005750	cellular_component	mitochondrial respiratory chain complex III
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0070469	cellular_component	respirasome
H	0005750	cellular_component	mitochondrial respiratory chain complex III
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005750	cellular_component	mitochondrial respiratory chain complex III
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0070469	cellular_component	respirasome
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005750	cellular_component	mitochondrial respiratory chain complex III
K	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K	0070469	cellular_component	respirasome
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0046872	molecular_function	metal ion binding
M	0070469	cellular_component	respirasome
N	0004222	molecular_function	metalloendopeptidase activity
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0006508	biological_process	proteolysis
N	0046872	molecular_function	metal ion binding
N	0070469	cellular_component	respirasome
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005750	cellular_component	mitochondrial respiratory chain complex III
O	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
O	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
O	0009055	molecular_function	electron transfer activity
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0020037	molecular_function	heme binding
O	0022904	biological_process	respiratory electron transport chain
O	0031966	cellular_component	mitochondrial membrane
O	0045275	cellular_component	respiratory chain complex III
O	0046872	molecular_function	metal ion binding
O	0048039	molecular_function	ubiquinone binding
O	0070469	cellular_component	respirasome
O	1902600	biological_process	proton transmembrane transport
P	0009055	molecular_function	electron transfer activity
P	0020037	molecular_function	heme binding
Q	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
Q	0016020	cellular_component	membrane
Q	0051537	molecular_function	2 iron, 2 sulfur cluster binding
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005750	cellular_component	mitochondrial respiratory chain complex III
R	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R	0070469	cellular_component	respirasome
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005750	cellular_component	mitochondrial respiratory chain complex III
S	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S	0070469	cellular_component	respirasome
T	0005750	cellular_component	mitochondrial respiratory chain complex III
T	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
U	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005750	cellular_component	mitochondrial respiratory chain complex III
V	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
V	0070469	cellular_component	respirasome
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0005750	cellular_component	mitochondrial respiratory chain complex III
W	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
W	0070469	cellular_component	respirasome

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM C 380

Chain	Residue
C	GLN44
C	GLY130
C	TYR131
C	PRO134
C	HIS182
C	PHE183
C	PRO186
C	ILE45
C	GLY48
C	LEU49
C	LEU51
C	ALA52
C	ARG80
C	HIS83
C	THR126

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM C 381

Chain	Residue
C	TRP31
C	GLY34
C	SER35
C	LEU37
C	HIS97
C	ARG100
C	SER106
C	PHE109
C	TRP113
C	GLY116
C	VAL117
C	LEU119
C	LEU120
C	HIS196
C	LEU197
C	LEU200
C	SER205
C	ASN206

---

site_id	AC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC D 242

Chain	Residue
D	VAL36
D	CYS37
D	SER39
D	CYS40
D	HIS41
D	LEU113
D	ARG120
D	TYR126
D	PHE153
D	ILE158
D	GLY159
D	MET160
D	ILE164
D	LEU190

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM O 380

Chain	Residue
O	LEU41
O	GLN44
O	ILE45
O	GLY48
O	LEU49
O	LEU51
O	ALA52
O	ARG80
O	HIS83
O	THR126
O	GLY130
O	TYR131
O	PRO134
O	HIS182
O	PHE183
O	PRO186

---

site_id	AC5
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM O 381

Chain	Residue
O	TRP31
O	GLY34
O	SER35
O	LEU37
O	GLY38
O	LEU94
O	HIS97
O	ARG100
O	SER106
O	PHE109
O	THR112
O	TRP113
O	GLY116
O	VAL117
O	LEU119
O	LEU120
O	HIS196
O	LEU197
O	LEU200
O	SER205
O	ASN206

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC P 242

Chain	Residue
P	VAL36
P	CYS37
P	CYS40
P	HIS41
P	ASN105
P	LEU113
P	ARG120
P	TYR126
P	VAL127
P	PHE153
P	ILE158
P	GLY159
P	MET160
P	ILE164
P	LEU190

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FES Q 197

Chain	Residue
Q	CYS139
Q	HIS141
Q	LEU142
Q	GLY143
Q	CYS144
Q	CYS158
Q	CYS160
Q	HIS161
Q	SER163

---

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryensnnlGtSHLLRLAsSlTT

Chain	Residue	Details
B	GLY54-THR77

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:9651245

Chain	Residue	Details
K	MET1-GLN12
O	TRP77-VAL98
O	TRP113-LEU133
O	PHE178-LEU198
O	ILE226-ALA246
O	LEU288-HIS308
O	LEU320-GLY340
O	TYR347-PRO367
W	MET1-GLN12
P	HIS121
P	GLU124
C	ILE226-ALA246
C	LEU288-HIS308
C	LEU320-GLY340
C	TYR347-PRO367
O	PHE33-MET53

---

site_id	SWS_FT_FI2
Number of Residues	44
Details	TRANSMEM: Helical => ECO:0000269|PubMed:9651245

Chain	Residue	Details
K	LEU13-ALA35
W	LEU13-ALA35
F	GLU96
R	TRP19
R	TYR83
R	GLU96

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:9651245

Chain	Residue	Details
K	THR36-ASP56
W	THR36-ASP56
R	GLU78
R	SER88

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:9651245, ECO:0007744|PDB:1BE3, ECO:0007744|PDB:1BGY

Chain	Residue	Details
E	CYS139
Q	SER163
E	HIS141
E	CYS158
E	HIS161
E	SER163
Q	CYS139
Q	HIS141
Q	CYS158
Q	HIS161

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15312779, ECO:0000269|PubMed:16024040, ECO:0007744|PDB:1PP9, ECO:0007744|PDB:1SQV, ECO:0007744|PDB:2A06, ECO:0007744|PDB:2YBB

Chain	Residue	Details
C	HIS201
O	HIS201

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
Q	HIS161

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
A	GLU60

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
M	GLU60

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
B	ARG70

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
N	ARG70

---