1BGV

GLUTAMATE DEHYDROGENASE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
A	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
A	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0006537	biological_process	glutamate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
A	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
A	0055114	biological_process	obsolete oxidation-reduction process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GLU A 501

Chain	Residue
A	LYS89
A	HOH502
A	GLY91
A	GLN110
A	LYS113
A	LYS125
A	ALA163
A	GLY164
A	ASP165
A	SER380

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Functional Information from PROSITE/UniProt

site_id	PS00074
Number of Residues	14
Details	GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LpmGGAKgGsdfDP

Chain	Residue	Details
A	LEU119-PRO132

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10011","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8263917","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8263917","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Important for catalysis","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1hrd

Chain	Residue	Details
A	LYS125
A	ASP165

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site_id	MCSA1
Number of Residues	2
Details	M-CSA 579

Chain	Residue	Details
A	LYS125	electrostatic stabiliser, proton acceptor, proton donor
A	ASP165	proton acceptor, proton donor

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