1BGK
SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0015459 | molecular_function | potassium channel regulator activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0042151 | cellular_component | nematocyst |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Peptide: {"description":"Kappa-actitoxin-Bgr1a","featureId":"PRO_0000044864","evidences":[{"source":"PubMed","id":"8098956","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"ShKT","evidences":[{"source":"PROSITE-ProRule","id":"PRU01005","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Region: {"description":"Crucial for binding to potassium channels","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9020148","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Key residue for binding Kv1.2 and Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9020148","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Key residue for binding Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for binding Kv1.2","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for binding Kv1.2 and Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9020148","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Site: {"description":"Important for binding Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Key residue for binding Kv1.1 and Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Site: {"description":"Key residue for binding Kv1.1, Kv1.2 and Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9020148","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for binding Kv1.1 and key residue for binding Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for binding Kv1.1, Kv1.2 and key residue for binding Kv1.3","evidences":[{"source":"PubMed","id":"10585444","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9020148","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
