Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000162 | biological_process | tryptophan biosynthetic process |
A | 0004834 | molecular_function | tryptophan synthase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005829 | cellular_component | cytosol |
A | 0006568 | biological_process | tryptophan metabolic process |
A | 0016829 | molecular_function | lyase activity |
B | 0000162 | biological_process | tryptophan biosynthetic process |
B | 0004834 | molecular_function | tryptophan synthase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0006568 | biological_process | tryptophan metabolic process |
B | 0016829 | molecular_function | lyase activity |
B | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE K B 400 |
Chain | Residue |
B | GLY232 |
B | GLY268 |
B | PHE306 |
B | SER308 |
B | HOH454 |
site_id | AC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE IPL A 273 |
Chain | Residue |
A | ASN60 |
A | ILE64 |
A | LEU100 |
A | TYR102 |
A | TYR175 |
A | GLY211 |
A | GLY213 |
A | GLY234 |
A | SER235 |
A | HOH574 |
A | HOH575 |
A | PHE22 |
A | ALA59 |
site_id | AC3 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE PLS B 398 |
Chain | Residue |
B | HIS86 |
B | LYS87 |
B | THR110 |
B | GLY111 |
B | ALA112 |
B | GLN114 |
B | HIS115 |
B | LEU166 |
B | THR190 |
B | GLY232 |
B | GLY233 |
B | GLY234 |
B | SER235 |
B | ASN236 |
B | ALA302 |
B | GLY303 |
B | LEU304 |
B | SER377 |
B | HOH456 |
B | HOH458 |
B | HOH548 |
site_id | NUA |
Number of Residues | 1 |
Details | SUBSTRATE ANALOG BOUND TO THE ALPHA ACTIVE SITE. |
site_id | NUB |
Number of Residues | 1 |
Details | REACTION INTERMEDIATE BOUND TO THE BETA ACTIVE SITE. |
Functional Information from PROSITE/UniProt
site_id | PS00168 |
Number of Residues | 15 |
Details | TRP_SYNTHASE_BETA Tryptophan synthase beta chain pyridoxal-phosphate attachment site. LlHgGAHKtNqvLgQ |
Chain | Residue | Details |
B | LEU80-GLN94 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: N6-(pyridoxal phosphate)lysine |
Chain | Residue | Details |
B | THR88 | |
A | ASN60 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a50 |
Chain | Residue | Details |
B | HIS86 | |
B | LYS87 | |
B | LYS167 | |
B | ASP305 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1a50 |
Chain | Residue | Details |
B | LYS87 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a50 |
Chain | Residue | Details |
B | SER377 | |
B | LYS87 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a50 |
Chain | Residue | Details |
A | TYR175 | |
A | GLU49 | |
A | ASN60 | |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 383 |
Chain | Residue | Details |
B | THR88 | electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor |
B | THR110 | |
B | GLY378 | hydrogen bond donor |