1BCJ

MANNOSE-BINDING PROTEIN-A MUTANT (QPDWGHV) COMPLEXED WITH N-ACETYL-D-GALACTOSAMINE

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0001867	biological_process	complement activation, lectin pathway
1	0005537	molecular_function	mannose binding
2	0001867	biological_process	complement activation, lectin pathway
2	0005537	molecular_function	mannose binding
3	0001867	biological_process	complement activation, lectin pathway
3	0005537	molecular_function	mannose binding

Functional Information from PDB Data

site_id	11
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
1	ASP161
1	GLU165
1	ASP188
1	GLU198
1	ASP199
1	CA227
1	HOH237

---

site_id	12
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
2	ASP161
2	GLU165
2	ASP188
2	GLU198
2	ASP199
2	CA227
2	HOH303

---

site_id	13
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
3	ASP161
3	GLU165
3	ASP188
3	GLY193
3	LEU194
3	CA227
3	HOH236

---

site_id	21
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
1	GLU198
1	ASN210
1	ASP211
1	CA2
1	NGA1
1	GLN185
1	ASP187

---

site_id	22
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
2	GLN185
2	ASP187
2	GLU198
2	ASN210
2	ASP211
2	CA2
2	NGA1

---

site_id	23
Number of Residues	7
Details	CA BINDING SITE.

Chain	Residue
3	GLN185
3	ASP187
3	GLU198
3	ASN210
3	ASP211
3	CA2
3	NGA1

---

site_id	31
Number of Residues	5
Details	CA BINDING SITE.

Chain	Residue
1	GLU84
1	CA3
1	HOH229
1	HOH231
1	HOH236

---

site_id	32
Number of Residues	6
Details	CA BINDING SITE.

Chain	Residue
2	GLU165
2	ASP199
2	CA3
2	HOH228
2	HOH249
2	HOH302

---

site_id	33
Number of Residues	5
Details	CA BINDING SITE.

Chain	Residue
3	GLU84
3	CA3
3	HOH230
1	HOH239
3	HOH241

---

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	23
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVhivdngl.....WNDISCqasht.AVC

Chain	Residue	Details
1	CYS200-CYS222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB

Chain	Residue	Details
1	ASP161
1	GLU165
1	ASP188
1	ASP199
2	GLU165
2	ASP188
2	ASP199
3	ASP161
3	GLU165
3	ASP188
3	ASP199
2	ASP161

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB

Chain	Residue	Details
1	GLN185
1	ASP187
1	GLU198
1	ASN210
2	GLN185
2	ASP187
2	GLU198
2	ASN210
2	ASP211
3	GLN185
3	ASP187
3	GLU198
3	ASN210
3	ASP211
1	ASP211

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