Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1BCC

CYTOCHROME BC1 COMPLEX FROM CHICKEN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0016020	cellular_component	membrane
A	0032991	cellular_component	protein-containing complex
A	0046872	molecular_function	metal ion binding
B	0004222	molecular_function	metalloendopeptidase activity
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006508	biological_process	proteolysis
B	0016020	cellular_component	membrane
B	0045275	cellular_component	respiratory chain complex III
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0006979	biological_process	response to oxidative stress
C	0008121	molecular_function	quinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0022904	biological_process	respiratory electron transport chain
C	0045275	cellular_component	respiratory chain complex III
C	0046872	molecular_function	metal ion binding
C	1902600	biological_process	proton transmembrane transport
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
E	0008121	molecular_function	quinol-cytochrome-c reductase activity
E	0016020	cellular_component	membrane
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0016020	cellular_component	membrane
F	0045275	cellular_component	respiratory chain complex III
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0016020	cellular_component	membrane
G	0021539	biological_process	subthalamus development
G	0021548	biological_process	pons development
G	0021680	biological_process	cerebellar Purkinje cell layer development
G	0021766	biological_process	hippocampus development
G	0021794	biological_process	thalamus development
G	0021854	biological_process	hypothalamus development
G	0021860	biological_process	pyramidal neuron development
G	0030901	biological_process	midbrain development
G	0045275	cellular_component	respiratory chain complex III
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0016020	cellular_component	membrane
J	0045275	cellular_component	respiratory chain complex III

Functional Information from PDB Data

site_id	BHI
Number of Residues	2
Details	HISTIDINE AXIAL LIGANDS OF HIGH POTENTIAL HEME OF CYTOCHROME B.

Chain	Residue
C	HIS98
C	HIS197

site_id	BLO
Number of Residues	2
Details	HISTIDINE AXIAL LIGANDS OF LOW POTENTIAL HEME OF CYTOCHROME B.

Chain	Residue
C	HIS84
C	HIS183

site_id	C1H
Number of Residues	2
Details	HISTIDINE AND METHIONINE AXIAL LIGANDS OF HIGH POTENTIAL HEME OF CYTOCHROME C1.

Chain	Residue
D	HIS41
D	MET160

site_id	FES
Number of Residues	4
Details	HISTIDINE AND CYSTINE LIGANDS OF THE RIESKE IRON-SULFUR CLUSTER.

Chain	Residue
E	HIS161
E	CYS139
E	HIS141
E	CYS158

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryenssnlGtSHLLRLAsSlTT

Chain	Residue	Details
B	GLY54-THR77

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	158
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P31930","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZ13","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CZ13","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q68FY0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9DB77","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	161
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"20025846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21575592","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22690928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9565029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3L70","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20025846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21575592","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22690928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9565029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L70","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L75","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TGU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"20025846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21575592","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22690928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9565029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L70","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L75","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TGU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"20025846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21575592","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22690928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9565029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L70","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L75","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TGU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21575592","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22690928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9565029","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BCC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L72","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	329
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	33
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	101
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	2
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BGY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BGY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BE3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	85
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9651245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BGY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D855","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9D855","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q9CQ69","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P99028","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
E	HIS161

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
A	GLU60

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndo

Chain	Residue	Details
B	ARG70

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)