Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1BAR

THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0001759biological_processorgan induction
A0005104molecular_functionfibroblast growth factor receptor binding
A0005178molecular_functionintegrin binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005938cellular_componentcell cortex
A0008083molecular_functiongrowth factor activity
A0008201molecular_functionheparin binding
A0008284biological_processpositive regulation of cell population proliferation
A0008543biological_processfibroblast growth factor receptor signaling pathway
A0010595biological_processpositive regulation of endothelial cell migration
A0022008biological_processneurogenesis
A0030154biological_processcell differentiation
A0030324biological_processlung development
A0030334biological_processregulation of cell migration
A0030335biological_processpositive regulation of cell migration
A0031012cellular_componentextracellular matrix
A0032148biological_processactivation of protein kinase B activity
A0034605biological_processcellular response to heat
A0042060biological_processwound healing
A0043410biological_processpositive regulation of MAPK cascade
A0044548molecular_functionS100 protein binding
A0045542biological_processpositive regulation of cholesterol biosynthetic process
A0045766biological_processpositive regulation of angiogenesis
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0050673biological_processepithelial cell proliferation
A0050679biological_processpositive regulation of epithelial cell proliferation
A0051781biological_processpositive regulation of cell division
A0060681biological_processbranch elongation involved in ureteric bud branching
A0070374biological_processpositive regulation of ERK1 and ERK2 cascade
A0072163biological_processmesonephric epithelium development
A1901509biological_processregulation of endothelial tube morphogenesis
A1902533biological_processpositive regulation of intracellular signal transduction
A1903672biological_processpositive regulation of sprouting angiogenesis
A2000544biological_processregulation of endothelial cell chemotaxis to fibroblast growth factor
B0001525biological_processangiogenesis
B0001759biological_processorgan induction
B0005104molecular_functionfibroblast growth factor receptor binding
B0005178molecular_functionintegrin binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005938cellular_componentcell cortex
B0008083molecular_functiongrowth factor activity
B0008201molecular_functionheparin binding
B0008284biological_processpositive regulation of cell population proliferation
B0008543biological_processfibroblast growth factor receptor signaling pathway
B0010595biological_processpositive regulation of endothelial cell migration
B0022008biological_processneurogenesis
B0030154biological_processcell differentiation
B0030324biological_processlung development
B0030334biological_processregulation of cell migration
B0030335biological_processpositive regulation of cell migration
B0031012cellular_componentextracellular matrix
B0032148biological_processactivation of protein kinase B activity
B0034605biological_processcellular response to heat
B0042060biological_processwound healing
B0043410biological_processpositive regulation of MAPK cascade
B0044548molecular_functionS100 protein binding
B0045542biological_processpositive regulation of cholesterol biosynthetic process
B0045766biological_processpositive regulation of angiogenesis
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0050673biological_processepithelial cell proliferation
B0050679biological_processpositive regulation of epithelial cell proliferation
B0051781biological_processpositive regulation of cell division
B0060681biological_processbranch elongation involved in ureteric bud branching
B0070374biological_processpositive regulation of ERK1 and ERK2 cascade
B0072163biological_processmesonephric epithelium development
B1901509biological_processregulation of endothelial tube morphogenesis
B1902533biological_processpositive regulation of intracellular signal transduction
B1903672biological_processpositive regulation of sprouting angiogenesis
B2000544biological_processregulation of endothelial cell chemotaxis to fibroblast growth factor
Functional Information from PROSITE/UniProt
site_idPS00247
Number of Residues24
DetailsHBGF_FGF HBGF/FGF family signature. GlLyGsqtpne.EClFlErleengY
ChainResidueDetails
AGLY71-TYR94

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
ALYS9
AILE98
BLYS9
BILE98

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon