Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004397 | molecular_function | histidine ammonia-lyase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006547 | biological_process | L-histidine metabolic process |
| A | 0006548 | biological_process | L-histidine catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016841 | molecular_function | ammonia-lyase activity |
| A | 0019556 | biological_process | L-histidine catabolic process to glutamate and formamide |
| A | 0019557 | biological_process | L-histidine catabolic process to glutamate and formate |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 510 |
| Chain | Residue |
| A | TYR53 |
| A | ASN195 |
| A | GLN277 |
| A | TYR280 |
| A | ARG283 |
| A | ASN313 |
| A | PHE329 |
| A | HOH668 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 511 |
| Chain | Residue |
| A | ILE55 |
| A | THR57 |
| A | LEU72 |
| A | GLN76 |
| A | LEU79 |
| A | ALA187 |
| A | LYS188 |
| A | LEU191 |
| A | GLY54 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. GEGkaRYKGQWLSA |
| Chain | Residue | Details |
| A | GLY160-GLU173 | |
| site_id | PS00488 |
| Number of Residues | 17 |
| Details | PAL_HISTIDASE Phenylalanine and histidine ammonia-lyases signature. GSVGASGDLaPLAhmsL |
| Chain | Residue | Details |
| A | GLY138-LEU156 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP145 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CROSSLNK: 5-imidazolinone (Ala-Gly) |
| Chain | Residue | Details |
| A | MDO142 | |
| A | LEU146 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10220322 |
| Chain | Residue | Details |
| A | ALA142 | |
| A | TYR280 | |
| A | SER143 | |
| A | GLU414 | |
| A | GLY144 | |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 417 |
| Chain | Residue | Details |
| A | TYR53 | electrostatic stabiliser |
| A | HIS83 | electrostatic stabiliser |
| A | THR197 | activator |
| A | LEU282 | proton shuttle (general acid/base) |
| A | GLN285 | electrostatic stabiliser |
| A | ALA331 | electrostatic stabiliser |
| A | HIS416 | proton shuttle (general acid/base) |
