1B8A
ASPARTYL-TRNA SYNTHETASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 600 |
| Chain | Residue |
| A | ATP500 |
| A | HOH2198 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2201 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 601 |
| Chain | Residue |
| A | HOH2250 |
| A | HOH2251 |
| A | GLU361 |
| A | SER364 |
| A | ATP500 |
| A | MN602 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 602 |
| Chain | Residue |
| A | GLU361 |
| A | ATP500 |
| A | MN601 |
| A | HOH2248 |
| A | HOH2249 |
| A | HOH2250 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 1600 |
| Chain | Residue |
| B | ATP1500 |
| B | HOH2194 |
| B | HOH2195 |
| B | HOH2196 |
| B | HOH2197 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1601 |
| Chain | Residue |
| B | GLU1361 |
| B | ATP1500 |
| B | MN1602 |
| B | HOH2252 |
| B | HOH2254 |
| B | HOH2293 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 1602 |
| Chain | Residue |
| B | GLU1361 |
| B | SER1364 |
| B | ATP1500 |
| B | MN1601 |
| B | HOH2253 |
| B | HOH2254 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP A 500 |
| Chain | Residue |
| A | ARG214 |
| A | GLU216 |
| A | ARG222 |
| A | HIS223 |
| A | LEU224 |
| A | GLU361 |
| A | ILE362 |
| A | SER363 |
| A | SER364 |
| A | GLY407 |
| A | GLY409 |
| A | ARG412 |
| A | MN600 |
| A | MN601 |
| A | MN602 |
| A | HOH2148 |
| A | HOH2191 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH3114 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ATP B 1500 |
| Chain | Residue |
| B | ARG1214 |
| B | GLU1216 |
| B | HIS1223 |
| B | LEU1224 |
| B | ALA1227 |
| B | GLU1361 |
| B | ILE1362 |
| B | SER1363 |
| B | SER1364 |
| B | GLY1407 |
| B | GLY1409 |
| B | ARG1412 |
| B | MN1600 |
| B | MN1601 |
| B | MN1602 |
| B | HOH2123 |
| B | HOH2196 |
| B | HOH2197 |
| B | HOH2987 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Region: {"description":"Aspartate"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for tRNA discrimination"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | ASP231 | |
| A | ARG214 | |
| A | ARG412 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | ARG1214 | |
| B | ASP1231 | |
| B | ARG1412 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | ARG214 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | ARG1214 |
