1B47
STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001784 | molecular_function | phosphotyrosine residue binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
| A | 0023051 | biological_process | regulation of signaling |
| B | 0001784 | molecular_function | phosphotyrosine residue binding |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0007166 | biological_process | cell surface receptor signaling pathway |
| B | 0023051 | biological_process | regulation of signaling |
| C | 0001784 | molecular_function | phosphotyrosine residue binding |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0007166 | biological_process | cell surface receptor signaling pathway |
| C | 0023051 | biological_process | regulation of signaling |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 351 |
| Chain | Residue |
| A | ASP229 |
| A | THR231 |
| A | ASN233 |
| A | TYR235 |
| A | GLU240 |
| A | HOH383 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 351 |
| Chain | Residue |
| B | TYR235 |
| B | GLU240 |
| B | HOH489 |
| B | ASP229 |
| B | THR231 |
| B | ASN233 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 351 |
| Chain | Residue |
| C | ASP229 |
| C | THR231 |
| C | ASN233 |
| C | TYR235 |
| C | GLU240 |
| C | HOH443 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 384 |
| Details | Region: {"description":"4H"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 216 |
| Details | Region: {"description":"EF-hand-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1B47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CBL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
