1AXD
STRUCTURE OF GLUTATHIONE S-TRANSFERASE-I BOUND WITH THE LIGAND LACTOYLGLUTATHIONE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0009635 | biological_process | response to herbicide |
| A | 0009751 | biological_process | response to salicylic acid |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0043295 | molecular_function | glutathione binding |
| B | 0000302 | biological_process | response to reactive oxygen species |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009410 | biological_process | response to xenobiotic stimulus |
| B | 0009635 | biological_process | response to herbicide |
| B | 0009751 | biological_process | response to salicylic acid |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042542 | biological_process | response to hydrogen peroxide |
| B | 0043295 | molecular_function | glutathione binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR CHAIN C OF LACTOYLGLUTATHIONE |
| Chain | Residue |
| A | SER11 |
| A | SER67 |
| A | ARG68 |
| A | HOH230 |
| C | HOH6 |
| C | HOH10 |
| C | HOH57 |
| A | ASN13 |
| A | PHE35 |
| A | HIS40 |
| A | LYS41 |
| A | GLN53 |
| A | VAL54 |
| A | PRO55 |
| A | GLU66 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR CHAIN D OF LACTOYLGLUTATHIONE |
| Chain | Residue |
| B | SER11 |
| B | ASN13 |
| B | PHE35 |
| B | HIS40 |
| B | LYS41 |
| B | GLN53 |
| B | VAL54 |
| B | PRO55 |
| B | GLU66 |
| B | SER67 |
| B | HOH272 |
| D | HOH145 |
| D | HOH163 |
| D | HOH237 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 162 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | GLY7 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | GLY7 |
