1AW1
TRIOSEPHOSPHATE ISOMERASE OF VIBRIO MARINUS COMPLEXED WITH 2-PHOSPHOGLYCOLATE
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004807 | molecular_function | triose-phosphate isomerase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006094 | biological_process | gluconeogenesis |
A | 0006096 | biological_process | glycolytic process |
A | 0016853 | molecular_function | isomerase activity |
A | 0019563 | biological_process | glycerol catabolic process |
A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
B | 0004807 | molecular_function | triose-phosphate isomerase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006094 | biological_process | gluconeogenesis |
B | 0006096 | biological_process | glycolytic process |
B | 0016853 | molecular_function | isomerase activity |
B | 0019563 | biological_process | glycerol catabolic process |
B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
D | 0004807 | molecular_function | triose-phosphate isomerase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0006094 | biological_process | gluconeogenesis |
D | 0006096 | biological_process | glycolytic process |
D | 0016853 | molecular_function | isomerase activity |
D | 0019563 | biological_process | glycerol catabolic process |
D | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
E | 0004807 | molecular_function | triose-phosphate isomerase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0005829 | cellular_component | cytosol |
E | 0006094 | biological_process | gluconeogenesis |
E | 0006096 | biological_process | glycolytic process |
E | 0016853 | molecular_function | isomerase activity |
E | 0019563 | biological_process | glycerol catabolic process |
E | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
G | 0004807 | molecular_function | triose-phosphate isomerase activity |
G | 0005737 | cellular_component | cytoplasm |
G | 0005829 | cellular_component | cytosol |
G | 0006094 | biological_process | gluconeogenesis |
G | 0006096 | biological_process | glycolytic process |
G | 0016853 | molecular_function | isomerase activity |
G | 0019563 | biological_process | glycerol catabolic process |
G | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
H | 0004807 | molecular_function | triose-phosphate isomerase activity |
H | 0005737 | cellular_component | cytoplasm |
H | 0005829 | cellular_component | cytosol |
H | 0006094 | biological_process | gluconeogenesis |
H | 0006096 | biological_process | glycolytic process |
H | 0016853 | molecular_function | isomerase activity |
H | 0019563 | biological_process | glycerol catabolic process |
H | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
J | 0004807 | molecular_function | triose-phosphate isomerase activity |
J | 0005737 | cellular_component | cytoplasm |
J | 0005829 | cellular_component | cytosol |
J | 0006094 | biological_process | gluconeogenesis |
J | 0006096 | biological_process | glycolytic process |
J | 0016853 | molecular_function | isomerase activity |
J | 0019563 | biological_process | glycerol catabolic process |
J | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
K | 0004807 | molecular_function | triose-phosphate isomerase activity |
K | 0005737 | cellular_component | cytoplasm |
K | 0005829 | cellular_component | cytosol |
K | 0006094 | biological_process | gluconeogenesis |
K | 0006096 | biological_process | glycolytic process |
K | 0016853 | molecular_function | isomerase activity |
K | 0019563 | biological_process | glycerol catabolic process |
K | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE PGA A 290 |
Chain | Residue |
A | LYS11 |
A | GLY235 |
A | GLY236 |
A | HOH309 |
A | HOH313 |
A | HOH314 |
A | HIS97 |
A | GLU169 |
A | ALA173 |
A | ILE174 |
A | GLY175 |
A | GLY213 |
A | SER214 |
A | LEU233 |
site_id | AC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PGA B 290 |
Chain | Residue |
B | LYS11 |
B | HIS97 |
B | GLU169 |
B | ALA173 |
B | ILE174 |
B | GLY175 |
B | GLY213 |
B | SER214 |
B | LEU233 |
B | GLY235 |
B | GLY236 |
B | HOH303 |
site_id | AC3 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE PGA D 290 |
Chain | Residue |
D | LYS11 |
D | HIS97 |
D | GLU169 |
D | ALA173 |
D | ILE174 |
D | GLY175 |
D | GLY213 |
D | SER214 |
D | LEU233 |
D | GLY235 |
D | GLY236 |
D | HOH308 |
D | HOH312 |
D | HOH313 |
site_id | AC4 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PGA E 290 |
Chain | Residue |
E | LYS11 |
E | HIS97 |
E | GLU169 |
E | ALA173 |
E | ILE174 |
E | GLY175 |
E | GLY213 |
E | SER214 |
E | LEU233 |
E | GLY235 |
E | GLY236 |
E | HOH303 |
site_id | AC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE PGA G 290 |
Chain | Residue |
G | LYS11 |
G | HIS97 |
G | GLU169 |
G | ALA173 |
G | ILE174 |
G | GLY175 |
G | GLY213 |
G | SER214 |
G | LEU233 |
G | GLY235 |
G | GLY236 |
G | HOH309 |
G | HOH313 |
G | HOH314 |
site_id | AC6 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PGA H 290 |
Chain | Residue |
H | LYS11 |
H | HIS97 |
H | GLU169 |
H | ALA173 |
H | ILE174 |
H | GLY175 |
H | GLY213 |
H | SER214 |
H | LEU233 |
H | GLY235 |
H | GLY236 |
H | HOH303 |
site_id | AC7 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE PGA J 290 |
Chain | Residue |
J | LYS11 |
J | HIS97 |
J | GLU169 |
J | ALA173 |
J | ILE174 |
J | GLY175 |
J | GLY213 |
J | SER214 |
J | LEU233 |
J | GLY235 |
J | GLY236 |
J | HOH310 |
J | HOH314 |
J | HOH315 |
site_id | AC8 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE PGA K 290 |
Chain | Residue |
K | SER214 |
K | LEU233 |
K | GLY235 |
K | GLY236 |
K | HOH303 |
K | LYS11 |
K | HIS97 |
K | GLU169 |
K | ALA173 |
K | ILE174 |
K | GLY175 |
K | GLY213 |
Functional Information from PROSITE/UniProt
site_id | PS00171 |
Number of Residues | 11 |
Details | TIM_1 Triosephosphate isomerase active site. AYEPIWAIGTG |
Chain | Residue | Details |
A | ALA167-GLY177 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | ACT_SITE: Electrophile => ECO:0000255|HAMAP-Rule:MF_00147, ECO:0000305|PubMed:9442062 |
Chain | Residue | Details |
A | HIS97 | |
B | HIS97 | |
D | HIS97 | |
E | HIS97 | |
G | HIS97 | |
H | HIS97 | |
J | HIS97 | |
K | HIS97 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00147 |
Chain | Residue | Details |
A | GLU169 | |
B | GLU169 | |
D | GLU169 | |
E | GLU169 | |
G | GLU169 | |
H | GLU169 | |
J | GLU169 | |
K | GLU169 |
site_id | SWS_FT_FI3 |
Number of Residues | 32 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00147, ECO:0000269|PubMed:9442062 |
Chain | Residue | Details |
A | ASN9 | |
D | GLY175 | |
D | SER214 | |
D | GLY235 | |
E | ASN9 | |
E | GLY175 | |
E | SER214 | |
E | GLY235 | |
G | ASN9 | |
G | GLY175 | |
G | SER214 | |
A | GLY175 | |
G | GLY235 | |
H | ASN9 | |
H | GLY175 | |
H | SER214 | |
H | GLY235 | |
J | ASN9 | |
J | GLY175 | |
J | SER214 | |
J | GLY235 | |
K | ASN9 | |
A | SER214 | |
K | GLY175 | |
K | SER214 | |
K | GLY235 | |
A | GLY235 | |
B | ASN9 | |
B | GLY175 | |
B | SER214 | |
B | GLY235 | |
D | ASN9 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
A | HIS97 | |
A | GLY175 | |
A | GLU169 | |
A | LYS11 | |
A | ASN9 |
site_id | CSA2 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
B | HIS97 | |
B | GLY175 | |
B | GLU169 | |
B | LYS11 | |
B | ASN9 |
site_id | CSA3 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
D | HIS97 | |
D | GLY175 | |
D | GLU169 | |
D | LYS11 | |
D | ASN9 |
site_id | CSA4 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
E | HIS97 | |
E | GLY175 | |
E | GLU169 | |
E | LYS11 | |
E | ASN9 |
site_id | CSA5 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
G | HIS97 | |
G | GLY175 | |
G | GLU169 | |
G | LYS11 | |
G | ASN9 |
site_id | CSA6 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
H | HIS97 | |
H | GLY175 | |
H | GLU169 | |
H | LYS11 | |
H | ASN9 |
site_id | CSA7 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
J | HIS97 | |
J | GLY175 | |
J | GLU169 | |
J | LYS11 | |
J | ASN9 |
site_id | CSA8 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1hti |
Chain | Residue | Details |
K | HIS97 | |
K | GLY175 | |
K | GLU169 | |
K | LYS11 | |
K | ASN9 |