1AVZ
V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Region: {"description":"Mediates dimerization, Nef-PTE1 interaction, Nef-induced CD4 and MHC-I down-regulation and enhancement of infectivity","evidences":[{"source":"PubMed","id":"19781555","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"PxxP; stabilizes the interaction of NEF/MHC-I with host AP1M1; necessary for MHC-I internalization","evidences":[{"source":"HAMAP-Rule","id":"MF_04078","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
