1AV8
RIBONUCLEOTIDE REDUCTASE R2 SUBUNIT FROM E. COLI
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
A | 0005506 | molecular_function | iron ion binding |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
A | 0009185 | biological_process | ribonucleoside diphosphate metabolic process |
A | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
A | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
A | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0042802 | molecular_function | identical protein binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
B | 0005506 | molecular_function | iron ion binding |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
B | 0009185 | biological_process | ribonucleoside diphosphate metabolic process |
B | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
B | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
B | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0042802 | molecular_function | identical protein binding |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FEO A 401 |
Chain | Residue |
A | ASP84 |
A | GLU115 |
A | HIS118 |
A | GLU204 |
A | GLU238 |
A | HIS241 |
A | HOH1201 |
A | HOH1202 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FEO B 402 |
Chain | Residue |
B | GLU115 |
B | HIS118 |
B | GLU204 |
B | GLU238 |
B | HIS241 |
B | HOH1203 |
B | HOH1204 |
B | ASP84 |
Functional Information from PROSITE/UniProt
site_id | PS00368 |
Number of Residues | 17 |
Details | RIBORED_SMALL Ribonucleotide reductase small subunit signature. SEt.IHSrSYthIirnIV |
Chain | Residue | Details |
A | SER114-VAL130 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | THR123 | |
B | THR123 |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
A | SER85 | |
B | ALA205 | |
B | ALA239 | |
B | LEU242 | |
A | THR116 | |
A | SER119 | |
A | ALA205 | |
A | ALA239 | |
A | LEU242 | |
B | SER85 | |
B | THR116 | |
B | SER119 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1xik |
Chain | Residue | Details |
A | TYR122 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1xik |
Chain | Residue | Details |
B | TYR122 |
site_id | MCSA1 |
Number of Residues | 2 |
Details | M-CSA 918 |
Chain | Residue | Details |
A | THR123 | pi-pi interaction, single electron relay |
A | GLU238 |
site_id | MCSA2 |
Number of Residues | 2 |
Details | M-CSA 918 |
Chain | Residue | Details |
B | THR123 | pi-pi interaction, single electron relay |
B | GLU238 |