Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0016920 | molecular_function | pyroglutamyl-peptidase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01333 |
| Number of Residues | 17 |
| Details | PYRASE_GLU Pyrrolidone-carboxylate peptidase glutamic acid active site. GqaGgrmqITpERVAiN |
| Chain | Residue | Details |
| A | GLY70-ASN86 | |
| site_id | PS01334 |
| Number of Residues | 15 |
| Details | PYRASE_CYS Pyrrolidone-carboxylate peptidase cysteine active site. IpAaVSyTAGtFVCN |
| Chain | Residue | Details |
| A | ILE131-ASN145 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU81 | |
| D | GLU711 | |
| D | CYS774 | |
| D | HIS798 | |
| A | CYS144 | |
| A | HIS168 | |
| B | GLU291 | |
| B | CYS354 | |
| B | HIS378 | |
| C | GLU501 | |
| C | CYS564 | |
| C | HIS588 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10196127, 8095933, 8655512 |
| Chain | Residue | Details |
| A | GLU81 | |
| A | CYS144 | |
| A | CYS144 | |
| A | ARG91 | |
| A | HIS168 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10196127, 8095933, 8655512 |
| Chain | Residue | Details |
| B | GLU291 | |
| B | CYS354 | |
| B | CYS354 | |
| B | HIS378 | |
| B | ARG301 | |
| site_id | CSA3 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10196127, 8095933, 8655512 |
| Chain | Residue | Details |
| C | HIS588 | |
| C | CYS564 | |
| C | CYS564 | |
| C | ARG511 | |
| C | GLU501 | |
| site_id | CSA4 |
| Number of Residues | 5 |
| Details | a catalytic site defined by CSA, PubMed 10196127, 8095933, 8655512 |
| Chain | Residue | Details |
| D | HIS798 | |
| D | CYS774 | |
| D | CYS774 | |
| D | ARG721 | |
| D | GLU711 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 633 |
| Chain | Residue | Details |
| A | GLU81 | electrostatic stabiliser |
| A | ARG91 | electrostatic stabiliser |
| A | CYS144 | electrostatic stabiliser |
| A | HIS168 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 633 |
| Chain | Residue | Details |
| B | GLU291 | electrostatic stabiliser |
| B | ARG301 | electrostatic stabiliser |
| B | CYS354 | electrostatic stabiliser |
| B | HIS378 | proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 633 |
| Chain | Residue | Details |
| C | GLU501 | electrostatic stabiliser |
| C | ARG511 | electrostatic stabiliser |
| C | CYS564 | electrostatic stabiliser |
| C | HIS588 | proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 4 |
| Details | M-CSA 633 |
| Chain | Residue | Details |
| D | GLU711 | electrostatic stabiliser |
| D | ARG721 | electrostatic stabiliser |
| D | CYS774 | electrostatic stabiliser |
| D | HIS798 | proton acceptor, proton donor |
