1AQY
ESTROGEN SULFOTRANSFERASE WITH PAP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004062 | molecular_function | aryl sulfotransferase activity |
| A | 0004304 | molecular_function | estrone sulfotransferase activity |
| A | 0005496 | molecular_function | steroid binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0007565 | biological_process | female pregnancy |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0008210 | biological_process | estrogen metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0050294 | molecular_function | steroid sulfotransferase activity |
| A | 0051923 | biological_process | sulfation |
| B | 0004062 | molecular_function | aryl sulfotransferase activity |
| B | 0004304 | molecular_function | estrone sulfotransferase activity |
| B | 0005496 | molecular_function | steroid binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0007565 | biological_process | female pregnancy |
| B | 0008146 | molecular_function | sulfotransferase activity |
| B | 0008210 | biological_process | estrogen metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0050294 | molecular_function | steroid sulfotransferase activity |
| B | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE A3P A 301 |
| Chain | Residue |
| A | LYS48 |
| A | THR227 |
| A | PHE229 |
| A | MET232 |
| A | PHE255 |
| A | MET256 |
| A | ARG257 |
| A | LYS258 |
| A | GLY259 |
| A | HOH330 |
| A | HOH366 |
| A | SER49 |
| A | HOH367 |
| A | HOH379 |
| A | GLY50 |
| A | THR51 |
| A | THR52 |
| A | TRP53 |
| A | ARG130 |
| A | SER138 |
| A | TYR193 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE A3P B 302 |
| Chain | Residue |
| B | LYS48 |
| B | SER49 |
| B | GLY50 |
| B | THR51 |
| B | THR52 |
| B | TRP53 |
| B | ARG130 |
| B | SER138 |
| B | TYR193 |
| B | THR227 |
| B | PHE229 |
| B | MET232 |
| B | PHE255 |
| B | MET256 |
| B | ARG257 |
| B | LYS258 |
| B | GLY259 |
| B | HOH341 |
| B | HOH344 |
| B | HOH392 |
| B | HOH393 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:9765259 |
| Chain | Residue | Details |
| A | HIS108 | |
| B | HIS108 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9360604, ECO:0000269|PubMed:9765259, ECO:0007744|PDB:1AQU, ECO:0007744|PDB:1AQY, ECO:0007744|PDB:1BO6 |
| Chain | Residue | Details |
| A | LYS48 | |
| B | TYR193 | |
| B | THR227 | |
| B | ARG257 | |
| A | ARG130 | |
| A | SER138 | |
| A | TYR193 | |
| A | THR227 | |
| A | ARG257 | |
| B | LYS48 | |
| B | ARG130 | |
| B | SER138 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9360604, ECO:0007744|PDB:1AQU |
| Chain | Residue | Details |
| A | LYS106 | |
| B | LYS106 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P52844 |
| Chain | Residue | Details |
| A | SER156 | |
| B | SER156 |
