1AQY

ESTROGEN SULFOTRANSFERASE WITH PAP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004062	molecular_function	aryl sulfotransferase activity
A	0004304	molecular_function	estrone sulfotransferase activity
A	0005496	molecular_function	steroid binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006068	biological_process	ethanol catabolic process
A	0006629	biological_process	lipid metabolic process
A	0006711	biological_process	estrogen catabolic process
A	0007565	biological_process	female pregnancy
A	0008146	molecular_function	sulfotransferase activity
A	0008210	biological_process	estrogen metabolic process
A	0008289	molecular_function	lipid binding
A	0016740	molecular_function	transferase activity
A	0031965	cellular_component	nuclear membrane
A	0045600	biological_process	positive regulation of fat cell differentiation
A	0047894	molecular_function	flavonol 3-sulfotransferase activity
A	0050294	molecular_function	steroid sulfotransferase activity
A	0050427	biological_process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
A	0051923	biological_process	sulfation
B	0004062	molecular_function	aryl sulfotransferase activity
B	0004304	molecular_function	estrone sulfotransferase activity
B	0005496	molecular_function	steroid binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006068	biological_process	ethanol catabolic process
B	0006629	biological_process	lipid metabolic process
B	0006711	biological_process	estrogen catabolic process
B	0007565	biological_process	female pregnancy
B	0008146	molecular_function	sulfotransferase activity
B	0008210	biological_process	estrogen metabolic process
B	0008289	molecular_function	lipid binding
B	0016740	molecular_function	transferase activity
B	0031965	cellular_component	nuclear membrane
B	0045600	biological_process	positive regulation of fat cell differentiation
B	0047894	molecular_function	flavonol 3-sulfotransferase activity
B	0050294	molecular_function	steroid sulfotransferase activity
B	0050427	biological_process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
B	0051923	biological_process	sulfation

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE A3P A 301

Chain	Residue
A	LYS48
A	THR227
A	PHE229
A	MET232
A	PHE255
A	MET256
A	ARG257
A	LYS258
A	GLY259
A	HOH330
A	HOH366
A	SER49
A	HOH367
A	HOH379
A	GLY50
A	THR51
A	THR52
A	TRP53
A	ARG130
A	SER138
A	TYR193

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE A3P B 302

Chain	Residue
B	LYS48
B	SER49
B	GLY50
B	THR51
B	THR52
B	TRP53
B	ARG130
B	SER138
B	TYR193
B	THR227
B	PHE229
B	MET232
B	PHE255
B	MET256
B	ARG257
B	LYS258
B	GLY259
B	HOH341
B	HOH344
B	HOH392
B	HOH393

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"9765259","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360604","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9765259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AQU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AQY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BO6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360604","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AQU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P52844","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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