Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006304 | biological_process | DNA modification |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0032259 | biological_process | methylation |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006304 | biological_process | DNA modification |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| B | 0009307 | biological_process | DNA restriction-modification system |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SFG A 500 |
| Chain | Residue |
| A | VAL21 |
| A | TYR108 |
| A | PHE146 |
| A | ALA47 |
| A | GLU71 |
| A | ILE72 |
| A | ASP89 |
| A | PHE90 |
| A | ASN105 |
| A | PRO106 |
| A | PRO107 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SFG B 500 |
| Chain | Residue |
| B | VAL21 |
| B | ALA47 |
| B | GLU71 |
| B | ILE72 |
| B | ASP89 |
| B | PHE90 |
| B | ASN105 |
| B | PRO106 |
| B | PRO107 |
| B | TYR108 |
| B | PHE146 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. ILGNPPY |
| Chain | Residue | Details |
| A | ILE102-TYR108 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR23 | |
| B | ASP89 | |
| B | PRO107 | |
| A | GLU45 | |
| A | GLU71 | |
| A | ASP89 | |
| A | PRO107 | |
| B | THR23 | |
| B | GLU45 | |
| B | GLU71 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for catalytic activity => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | ASN105 | |
| A | TYR108 | |
| B | ASN105 | |
| B | TYR108 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Important for catalytic activity; via amide nitrogen => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | PRO106 | |
| B | PRO106 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| A | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PHE196 | steric role |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| B | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| B | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| B | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| B | PHE196 | steric role |
