1APY
HUMAN ASPARTYLGLUCOSAMINIDASE
Functional Information from GO Data
Functional Information from PDB Data
| site_id | B1 |
| Number of Residues | 1 |
| Details | A CATALYTIC RESIDUE. |
| Chain | Residue |
| B | THR183 |
| site_id | D1 |
| Number of Residues | 1 |
| Details | A CATALYTIC RESIDUE. |
| Chain | Residue |
| D | THR183 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:8846222 |
| Chain | Residue | Details |
| B | THR183 | |
| D | THR183 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8846222 |
| Chain | Residue | Details |
| B | ARG211 | |
| B | THR234 | |
| D | ARG211 | |
| D | THR234 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8846222, ECO:0007744|PDB:1APY, ECO:0007744|PDB:1APZ |
| Chain | Residue | Details |
| B | ASN285 | |
| D | ASN285 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | a catalytic site defined by CSA, PubMed 8670796, 8500622, 8846222, 14616088 |
| Chain | Residue | Details |
| A | SER49 | |
| B | THR201 | |
| B | THR234 | |
| B | THR183 | |
| B | THR183 | |
| B | GLY235 |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | a catalytic site defined by CSA, PubMed 8670796, 8500622, 8846222, 14616088 |
| Chain | Residue | Details |
| C | SER49 | |
| D | THR201 | |
| D | THR234 | |
| D | THR183 | |
| D | THR183 | |
| D | GLY235 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 266 |
| Chain | Residue | Details |
| B | THR183 | covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | THR201 | activator, hydrogen bond donor |
| B | ARG211 | electrostatic stabiliser, hydrogen bond acceptor |
| B | THR234 | electrostatic stabiliser |
| B | GLY235 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 266 |
| Chain | Residue | Details |
| D | THR183 | covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| D | THR201 | activator, hydrogen bond donor |
| D | ARG211 | electrostatic stabiliser, hydrogen bond acceptor |
| D | THR234 | electrostatic stabiliser |
| D | GLY235 | electrostatic stabiliser, hydrogen bond donor |
