1ANP
SOLUTION CONFORMATION OF AN ATRIAL NATRIURETIC PEPTIDE VARIANT SELECTIVE FOR THE TYPE-A RECEPTOR
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | Peptide: {"description":"Atrial natriuretic peptide","featureId":"PRO_0000449729","evidences":[{"source":"PubMed","id":"10880574","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1826098","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3838202","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"6230082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Peptide: {"description":"Auriculin-B","featureId":"PRO_0000449730","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 23 |
| Details | Peptide: {"description":"Auriculin-A","featureId":"PRO_0000449731","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 23 |
| Details | Peptide: {"description":"Atriopeptin-3","featureId":"PRO_0000449732","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 22 |
| Details | Peptide: {"description":"Atriopeptin-2","featureId":"PRO_0000449733","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Peptide: {"description":"Atriopeptin-1","featureId":"PRO_0000449734","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Region: {"description":"Important for degradation of atrial natriuretic peptide by IDE","evidences":[{"source":"PubMed","id":"21098034","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by MME","evidences":[{"source":"PubMed","id":"2972276","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"2528951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
