Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1AN9

D-AMINO ACID OXIDASE COMPLEX WITH O-AMINOBENZOATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003884	molecular_function	D-amino-acid oxidase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006562	biological_process	proline catabolic process
A	0007586	biological_process	digestion
A	0016491	molecular_function	oxidoreductase activity
A	0019478	biological_process	D-amino acid catabolic process
A	0036088	biological_process	D-serine catabolic process
A	0042416	biological_process	dopamine biosynthetic process
A	0042995	cellular_component	cell projection
A	0045202	cellular_component	synapse
A	0046416	biological_process	D-amino acid metabolic process
A	0048786	cellular_component	presynaptic active zone
A	0055130	biological_process	D-alanine catabolic process
A	0070945	biological_process	neutrophil-mediated killing of gram-negative bacterium
A	0071949	molecular_function	FAD binding
B	0003884	molecular_function	D-amino-acid oxidase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005777	cellular_component	peroxisome
B	0005782	cellular_component	peroxisomal matrix
B	0005829	cellular_component	cytosol
B	0006562	biological_process	proline catabolic process
B	0007586	biological_process	digestion
B	0016491	molecular_function	oxidoreductase activity
B	0019478	biological_process	D-amino acid catabolic process
B	0036088	biological_process	D-serine catabolic process
B	0042416	biological_process	dopamine biosynthetic process
B	0042995	cellular_component	cell projection
B	0045202	cellular_component	synapse
B	0046416	biological_process	D-amino acid metabolic process
B	0048786	cellular_component	presynaptic active zone
B	0055130	biological_process	D-alanine catabolic process
B	0070945	biological_process	neutrophil-mediated killing of gram-negative bacterium
B	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	37
Details	BINDING SITE FOR RESIDUE FAD A 351

Chain	Residue
A	ILE6
A	THR44
A	THR45
A	ALA48
A	ALA49
A	GLY50
A	LEU51
A	ARG162
A	LYS163
A	VAL164
A	CYS181
A	GLY7
A	THR182
A	GLY183
A	TRP185
A	LEU189
A	ILE202
A	GLY281
A	ARG283
A	GLY312
A	GLY313
A	TYR314
A	ALA8
A	GLY315
A	LEU316
A	THR317
A	BE2352
A	HOH801
A	HOH810
A	HOH813
A	HOH850
A	GLY9
A	VAL10
A	ILE11
A	ALA36
A	ASP37
A	ARG38

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BE2 A 352

Chain	Residue
A	LEU51
A	ILE215
A	TYR224
A	TYR228
A	ARG283
A	GLY313
A	FAD351

site_id	AC3
Number of Residues	37
Details	BINDING SITE FOR RESIDUE FAD B 351

Chain	Residue
B	GLY7
B	ALA8
B	GLY9
B	VAL10
B	ILE11
B	ALA36
B	ASP37
B	ARG38
B	THR43
B	THR44
B	THR45
B	ALA48
B	ALA49
B	GLY50
B	LEU51
B	ARG162
B	LYS163
B	VAL164
B	CYS181
B	THR182
B	GLY183
B	TRP185
B	ILE202
B	GLY281
B	ARG283
B	GLY312
B	GLY313
B	TYR314
B	GLY315
B	LEU316
B	THR317
B	BE2352
B	HOH802
B	HOH807
B	HOH816
B	HOH823
B	HOH833

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BE2 B 352

Chain	Residue
B	TYR224
B	TYR228
B	ARG283
B	GLY313
B	FAD351

Functional Information from PROSITE/UniProt

site_id	PS00677
Number of Residues	19
Details	DAO D-amino acid oxidases signature. VIHNYGhGGyGltihwGcA

Chain	Residue	Details
A	VAL305-ALA323

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9153426, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH, ECO:0007744\|PDB:5WWV, ECO:0007744\|PDB:5WX2

Chain	Residue	Details
A	ALA8
B	ASP37
B	THR45
B	LEU51
B	VAL164
B	GLY312
B	GLY315
B	THR317
A	ASP37
A	THR45
A	LEU51
A	VAL164
A	GLY312
A	GLY315
A	THR317
B	ALA8

site_id	SWS_FT_FI2
Number of Residues	10
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P14920

Chain	Residue	Details
A	GLY9
B	ARG283
A	THR43
A	GLN53
A	THR182
A	ARG283
B	GLY9
B	THR43
B	GLN53
B	THR182

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:27648606, ECO:0007744\|PDB:4YJH

Chain	Residue	Details
A	VAL10
B	VAL10

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH, ECO:0007744\|PDB:5WX2

Chain	Residue	Details
A	ILE11
B	ILE11

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:9153426, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH, ECO:0007744\|PDB:5WWV, ECO:0007744\|PDB:5WX2

Chain	Residue	Details
A	ARG38
B	ARG38

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9153426, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:5WWV

Chain	Residue	Details
A	THR44
B	THR44

site_id	SWS_FT_FI7
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH

Chain	Residue	Details
A	ALA49
B	ALA49

site_id	SWS_FT_FI8
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9153426, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH, ECO:0007744\|PDB:5WWV

Chain	Residue	Details
A	GLY50
B	GLY50

site_id	SWS_FT_FI9
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0007744\|PDB:1EVI

Chain	Residue	Details
A	LYS163
B	LYS163

site_id	SWS_FT_FI10
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305\|PubMed:9399588, ECO:0007744\|PDB:1AN9

Chain	Residue	Details
A	TYR224
A	TYR228
B	TYR224
B	TYR228

site_id	SWS_FT_FI11
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:9153426, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH

Chain	Residue	Details
A	GLY313
B	GLY313

site_id	SWS_FT_FI12
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:10876160, ECO:0000269\|PubMed:24644036, ECO:0000269\|PubMed:27648606, ECO:0000269\|PubMed:30333894, ECO:0000269\|PubMed:8755502, ECO:0000269\|PubMed:9153426, ECO:0000269\|PubMed:9399588, ECO:0007744\|PDB:1AN9, ECO:0007744\|PDB:1DDO, ECO:0007744\|PDB:1EVI, ECO:0007744\|PDB:1KIF, ECO:0007744\|PDB:1VE9, ECO:0007744\|PDB:3WGT, ECO:0007744\|PDB:4YJD, ECO:0007744\|PDB:4YJF, ECO:0007744\|PDB:4YJG, ECO:0007744\|PDB:4YJH, ECO:0007744\|PDB:5WX2

Chain	Residue	Details
A	LEU316
B	LEU316

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1c0k

Chain	Residue	Details
A	GLY313

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1c0k

Chain	Residue	Details
B	GLY313

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)