1ALW

INHIBITOR AND CALCIUM BOUND DOMAIN VI OF PORCINE CALPAIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
B	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1

Chain	Residue
A	ALA107
A	ASP110
A	GLU112
A	GLU117
A	HOH538
A	HOH549

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 2

Chain	Residue
A	LYS156
A	GLU161
A	HOH544
A	ASP150
A	ASP152
A	THR154

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 3

Chain	Residue
A	ASP180
A	ASP182
A	SER184
A	THR186
A	GLU191
A	HOH547

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 4

Chain	Residue
A	ASP135
A	ASP223
A	ASP225
A	ASN226
A	HOH501
A	HOH506

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 5

Chain	Residue
B	ALA107
B	ASP110
B	GLU112
B	GLU117
B	HOH503
B	HOH514

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 6

Chain	Residue
B	ASP150
B	ASP152
B	THR154
B	LYS156
B	GLU161
B	HOH592

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 7

Chain	Residue
B	ASP180
B	ASP182
B	SER184
B	THR186
B	GLU191
B	HOH502

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 8

Chain	Residue
A	HOH532
B	ASP135
B	ASP223
B	ASP225
B	ASN226
B	HOH508

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ISA A 11

Chain	Residue
A	VAL125
A	HIS129
A	TRP166
A	ILE169
A	GLN173

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ISA B 12

Chain	Residue
B	VAL125
B	ARG128
B	HIS129
B	LYS170
B	GLN173
B	HOH602

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DSDTTGKLGfeEF

Chain	Residue	Details
A	ASP150-PHE162
A	ASP180-LEU192

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	Domain: {"description":"EF-hand 1; atypical","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	56
Details	Domain: {"description":"EF-hand 4","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	68
Details	Domain: {"description":"EF-hand 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q64537","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q64537","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P04632","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---