Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0005138 | molecular_function | interleukin-6 receptor binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006955 | biological_process | immune response |
| A | 0030154 | biological_process | cell differentiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 290 |
| Chain | Residue |
| A | PHE74 |
| A | GLN75 |
| A | LYS171 |
| A | GLN175 |
| A | ARG179 |
| A | HOH334 |
| A | HOH381 |
| A | HOH402 |
| A | HOH418 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 291 |
| Chain | Residue |
| A | ARG179 |
| A | ARG179 |
| A | HOH322 |
| A | HOH322 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 292 |
| Chain | Residue |
| A | ASN155 |
| A | GLN156 |
| A | HOH357 |
| A | HOH361 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 293 |
| Chain | Residue |
| A | ARG40 |
| A | CYS50 |
| A | GLU51 |
| A | GLU110 |
| A | HIS164 |
| A | ARG168 |
| A | HOH367 |
| A | HOH417 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE TLA A 300 |
| Chain | Residue |
| A | GLN175 |
| A | GLN175 |
| A | LEU178 |
| A | ARG179 |
| A | ARG179 |
| A | ARG182 |
| A | ARG182 |
| A | HOH306 |
Functional Information from PROSITE/UniProt
| site_id | PS00254 |
| Number of Residues | 26 |
| Details | INTERLEUKIN_6 Interleukin-6 / G-CSF / MGF signature. CfqsgfneetClvkiitGLleFevyL |
| Chain | Residue | Details |
| A | CYS73-LEU98 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER53 | |
| Chain | Residue | Details |
| A | ASN45 | |
