1AKM

ORNITHINE TRANSCARBAMYLASE FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004585	molecular_function	ornithine carbamoyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0006520	biological_process	amino acid metabolic process
A	0006526	biological_process	L-arginine biosynthetic process
A	0006591	biological_process	ornithine metabolic process
A	0008652	biological_process	amino acid biosynthetic process
A	0016597	molecular_function	amino acid binding
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0019240	biological_process	citrulline biosynthetic process
A	0042450	biological_process	L-arginine biosynthetic process via ornithine
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004585	molecular_function	ornithine carbamoyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006520	biological_process	amino acid metabolic process
B	0006526	biological_process	L-arginine biosynthetic process
B	0006591	biological_process	ornithine metabolic process
B	0008652	biological_process	amino acid biosynthetic process
B	0016597	molecular_function	amino acid binding
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0019240	biological_process	citrulline biosynthetic process
B	0042450	biological_process	L-arginine biosynthetic process via ornithine
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004585	molecular_function	ornithine carbamoyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006520	biological_process	amino acid metabolic process
C	0006526	biological_process	L-arginine biosynthetic process
C	0006591	biological_process	ornithine metabolic process
C	0008652	biological_process	amino acid biosynthetic process
C	0016597	molecular_function	amino acid binding
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0019240	biological_process	citrulline biosynthetic process
C	0042450	biological_process	L-arginine biosynthetic process via ornithine
C	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FeKdSTRT

Chain	Residue	Details
A	PHE51-THR58

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	33
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10747936","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9275160","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DUV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OTC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"2405164","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10747936","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	a catalytic site defined by CSA, PubMed 10813810, 9253409, 9852088, 2290837

Chain	Residue	Details
A	GLN136
A	CYS273
A	ASP231
A	ARG106
A	HIS133
A	ARG319

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site_id	CSA2
Number of Residues	6
Details	a catalytic site defined by CSA, PubMed 10813810, 9253409, 9852088, 2290837

Chain	Residue	Details
B	GLN136
B	CYS273
B	ASP231
B	ARG106
B	HIS133
B	ARG319

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site_id	CSA3
Number of Residues	6
Details	a catalytic site defined by CSA, PubMed 10813810, 9253409, 9852088, 2290837

Chain	Residue	Details
C	GLN136
C	CYS273
C	ASP231
C	ARG106
C	HIS133
C	ARG319

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